Neonatal Retinoblastoma.
Clin Perinatol
; 48(1): 53-70, 2021 03.
Article
en En
| MEDLINE
| ID: mdl-33583507
ABSTRACT
Retinoblastoma is the most common ocular malignancy of childhood. With an estimated 300 cases annually in the United States, retinoblastoma is nevertheless considered a rare tumor. Although retinoblastoma primarily affects younger children, diagnosis during the neonatal age range is less common. However, an understanding of patients at risk is critical for appropriate screening. Early detection and treatment by a multidisciplinary specialty team maximizes the chance for survival and ocular/vision salvage while minimizing treatment-related toxicity. Testing for alterations in the RB1 gene has become standard practice, and informs screening and genetic counseling recommendations for patients and their families.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Retinoblastoma
/
Neoplasias de la Retina
Tipo de estudio:
Diagnostic_studies
/
Guideline
/
Prognostic_studies
/
Screening_studies
Límite:
Child
/
Humans
/
Newborn
Idioma:
En
Revista:
Clin Perinatol
Año:
2021
Tipo del documento:
Article
País de afiliación:
Estados Unidos