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Autism Detection in Children by Combined Use of Gaze Preference and the M-CHAT-R in a Resource-Scarce Setting.
Jensen, Kelly; Noazin, Sassan; Bitterfeld, Leandra; Carcelen, Andrea; Vargas-Cuentas, Natalia I; Hidalgo, Daniela; Valenzuela, Alejandra; Roman-Gonzalez, Avid; Krebs, Casey; Clement, Vincent; Nolan, Cody; Barrientos, Franklin; Mendoza, Ardi Knobel; Noriega-Donis, Paola; Palacios, Claudia; Ramirez, Andrea; Vittet, Macarena; Hafeez, Emil; Torres-Viso, Mariana; Velarde, Myriam; Moulton, Lawrence H; Powers, Michael D; Gilman, Robert H; Zimic, Mirko.
Afiliación
  • Jensen K; Tulane University School of Medicine, New Orleans, LA, USA.
  • Noazin S; School of Public Health and Tropical Medicine, Tulane University, New Orleans, LA, USA.
  • Bitterfeld L; Louisiana State University, Baton Rouge, USA.
  • Carcelen A; Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA. snoazin1@jhu.edu.
  • Vargas-Cuentas NI; Johns Hopkins University School of Nursing, Baltimore, MD, USA.
  • Hidalgo D; USA Indian Health Service, Albuquerque, USA.
  • Valenzuela A; Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
  • Roman-Gonzalez A; Bioinformatics and Molecular Biology Laboratory, Research and Development Laboratory, Science and Philosophy Faculty, Universidad Peruana Cayetano Heredia, Lima, Peru.
  • Krebs C; Bioinformatics and Molecular Biology Laboratory, Research and Development Laboratory, Science and Philosophy Faculty, Universidad Peruana Cayetano Heredia, Lima, Peru.
  • Clement V; Psychology Faculty, Universidad Peruana Cayetano Heredia, Lima, Peru.
  • Nolan C; Bioinformatics and Molecular Biology Laboratory, Research and Development Laboratory, Science and Philosophy Faculty, Universidad Peruana Cayetano Heredia, Lima, Peru.
  • Barrientos F; Bioinformatics and Molecular Biology Laboratory, Research and Development Laboratory, Science and Philosophy Faculty, Universidad Peruana Cayetano Heredia, Lima, Peru.
  • Mendoza AK; Yale Child Study Center, Yale University School of Medicine, New Haven, CT, USA.
  • Noriega-Donis P; Psychology Faculty, Universidad Peruana Cayetano Heredia, Lima, Peru.
  • Palacios C; Weill Cornell Medical College, New York, NY, USA.
  • Ramirez A; Bioinformatics and Molecular Biology Laboratory, Research and Development Laboratory, Science and Philosophy Faculty, Universidad Peruana Cayetano Heredia, Lima, Peru.
  • Vittet M; Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ, USA.
  • Hafeez E; Johns Hopkins University Whiting School of Engineering, Baltimore, MD, USA.
  • Torres-Viso M; Bioinformatics and Molecular Biology Laboratory, Research and Development Laboratory, Science and Philosophy Faculty, Universidad Peruana Cayetano Heredia, Lima, Peru.
  • Velarde M; Bioinformatics and Molecular Biology Laboratory, Research and Development Laboratory, Science and Philosophy Faculty, Universidad Peruana Cayetano Heredia, Lima, Peru.
  • Moulton LH; Bioinformatics and Molecular Biology Laboratory, Research and Development Laboratory, Science and Philosophy Faculty, Universidad Peruana Cayetano Heredia, Lima, Peru.
  • Powers MD; Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
  • Gilman RH; CCSN: The Center for Children With Special Needs, Glastonbury, CT, USA.
  • Zimic M; IMLA: Instituto Medico Lengua Aprendazaje, Lima, Peru.
J Autism Dev Disord ; 51(3): 994-1006, 2021 Mar.
Article en En | MEDLINE | ID: mdl-33591436
ABSTRACT
Most children with autism spectrum disorder (ASD), in resource-limited settings (RLS), are diagnosed after the age of four. Our work confirmed and extended results of Pierce that eye tracking could discriminate between typically developing (TD) children and those with ASD. We demonstrated the initial 15 s was at least as discriminating as the entire video. We evaluated the GP-MCHAT-R, which combines the first 15 s of manually-coded gaze preference (GP) video with M-CHAT-R results on 73 TD children and 28 children with ASD, 36-99 months of age. The GP-MCHAT-R (AUC = 0.89 (95%CI 0.82-0.95)), performed significantly better than the MCHAT-R (AUC = 0.78 (95%CI 0.71-0.85)) and gaze preference (AUC = 0.76 (95%CI 0.64-0.88)) alone. This tool may enable early screening for ASD in RLS.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Tamizaje Masivo / Lista de Verificación / Fijación Ocular / Trastorno del Espectro Autista / Tecnología de Seguimiento Ocular / Recursos en Salud Tipo de estudio: Diagnostic_studies / Prognostic_studies / Screening_studies Aspecto: Patient_preference Límite: Child / Child, preschool / Female / Humans / Male País/Región como asunto: America do sul / Peru Idioma: En Revista: J Autism Dev Disord Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Tamizaje Masivo / Lista de Verificación / Fijación Ocular / Trastorno del Espectro Autista / Tecnología de Seguimiento Ocular / Recursos en Salud Tipo de estudio: Diagnostic_studies / Prognostic_studies / Screening_studies Aspecto: Patient_preference Límite: Child / Child, preschool / Female / Humans / Male País/Región como asunto: America do sul / Peru Idioma: En Revista: J Autism Dev Disord Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos