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Seizures and memory impairment induced by patient-derived anti-N-methyl-D-aspartate receptor antibodies in mice are attenuated by anakinra, an interleukin-1 receptor antagonist.
Taraschenko, Olga; Fox, Howard S; Zekeridou, Anastasia; Pittock, Sean J; Eldridge, Ember; Farukhuddin, Fnu; Al-Saleem, Fetweh; Devi Kattala, Chandana; Dessain, Scott K; Casale, George; Willcockson, Gregory; Dingledine, Raymond.
Afiliación
  • Taraschenko O; Department of Neurological Sciences, Division of Epilepsy, University of Nebraska Medical Center, Omaha, Nebraska, USA.
  • Fox HS; Department of Neurological Sciences, Division of Epilepsy, University of Nebraska Medical Center, Omaha, Nebraska, USA.
  • Zekeridou A; Departments of Neurology, Laboratory Medicine, and Pathology, Center for Multiple Sclerosis and Autoimmune Neurology, Mayo Clinic College of Medicine, Rochester, Minnesota, USA.
  • Pittock SJ; Departments of Neurology, Laboratory Medicine, and Pathology, Center for Multiple Sclerosis and Autoimmune Neurology, Mayo Clinic College of Medicine, Rochester, Minnesota, USA.
  • Eldridge E; Department of Neurological Sciences, Division of Epilepsy, University of Nebraska Medical Center, Omaha, Nebraska, USA.
  • Farukhuddin F; Department of Neurological Sciences, Division of Epilepsy, University of Nebraska Medical Center, Omaha, Nebraska, USA.
  • Al-Saleem F; Lankenau Institute for Medical Research, Wynnewood, Pennsylvania, USA.
  • Devi Kattala C; Lankenau Institute for Medical Research, Wynnewood, Pennsylvania, USA.
  • Dessain SK; Lankenau Institute for Medical Research, Wynnewood, Pennsylvania, USA.
  • Casale G; Department of Surgery, Division of Vascular Surgery, University of Nebraska Medical Center, Omaha, Nebraska, USA.
  • Willcockson G; Department of Surgery, Division of Vascular Surgery, University of Nebraska Medical Center, Omaha, Nebraska, USA.
  • Dingledine R; Department of Pharmacology and Chemical Biology, Emory University School of Medicine, Atlanta, Georgia, USA.
Epilepsia ; 62(3): 671-682, 2021 03.
Article en En | MEDLINE | ID: mdl-33596332
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Convulsiones / Autoanticuerpos / Receptores de Interleucina-1 / Receptores de N-Metil-D-Aspartato / Amnesia Anterógrada / Proteína Antagonista del Receptor de Interleucina 1 / Anticonvulsivantes Límite: Animals / Humans / Male Idioma: En Revista: Epilepsia Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Convulsiones / Autoanticuerpos / Receptores de Interleucina-1 / Receptores de N-Metil-D-Aspartato / Amnesia Anterógrada / Proteína Antagonista del Receptor de Interleucina 1 / Anticonvulsivantes Límite: Animals / Humans / Male Idioma: En Revista: Epilepsia Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos