Human iPSC-engineered cardiac tissue platform faithfully models important cardiac physiology.

de Lange, Willem J; Farrell, Emily T; Kreitzer, Caroline R; Jacobs, Derek R; Lang, Di; Glukhov, Alexey V; Ralphe, J Carter

de Lange, Willem J; Farrell, Emily T; Kreitzer, Caroline R; Jacobs, Derek R; Lang, Di; Glukhov, Alexey V; Ralphe, J Carter.

Afiliación

de Lange WJ; Department of Pediatrics, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin.
Farrell ET; Department of Pediatrics, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin.
Kreitzer CR; Department of Pediatrics, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin.
Jacobs DR; Department of Pediatrics, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin.
Lang D; Department of Medicine Cardiovascular Medicine, University of Wisconsin-Madison School of Medicine and Public Health, Madison, Wisconsin.
Glukhov AV; Department of Medicine Cardiovascular Medicine, University of Wisconsin-Madison School of Medicine and Public Health, Madison, Wisconsin.
Ralphe JC; Department of Pediatrics, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin.

Am J Physiol Heart Circ Physiol ; 320(4): H1670-H1686, 2021 04 01.

Article en En | MEDLINE | ID: mdl-33606581

Asunto(s)

Señalización del Calcio; Calcio/metabolismo; Diferenciación Celular; Células Madre Pluripotentes Inducidas/metabolismo; Miocitos Cardíacos/metabolismo; Ingeniería de Tejidos; Agonistas Adrenérgicos beta/farmacología; Señalización del Calcio/efectos de los fármacos; Línea Celular; Humanos; Células Madre Pluripotentes Inducidas/efectos de los fármacos; Células Madre Pluripotentes Inducidas/ultraestructura; Cinética; Contracción Miocárdica; Miocitos Cardíacos/efectos de los fármacos; Miocitos Cardíacos/ultraestructura; Fenotipo

Palabras clave

contractility; engineered cardiac tissue; human iPS cells; maturation; t-tubules

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Diferenciación Celular / Calcio / Señalización del Calcio / Ingeniería de Tejidos / Miocitos Cardíacos / Células Madre Pluripotentes Inducidas Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Am J Physiol Heart Circ Physiol Asunto de la revista: CARDIOLOGIA / FISIOLOGIA Año: 2021 Tipo del documento: Article

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