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The Roles of circRNAs in Liver Cancer Immunity.
Tang, Ying; Jiang, Mei; Jiang, Hai-Mei; Ye, Zeng Jie; Huang, Yu-Sheng; Li, Xiu-Shen; Qin, Bin-Yu; Zhou, Rui-Sheng; Pan, Hua-Feng; Zheng, Da-Yong.
Afiliación
  • Tang Y; Department of Oncology, Institute of Tumor, Guangzhou University of Chinese Medicine, Guangzhou, China.
  • Jiang M; Department of Oncology, Lingnan Medical Research Center of Guangzhou University of Chinese Medicine, Guangzhou, China.
  • Jiang HM; Department of Oncology, Guangzhou University of Chinese Medicine, Guangzhou, China.
  • Ye ZJ; Department of Oncology, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou University of Chinese Medicine, Guangzhou, China.
  • Huang YS; Department of Oncology, Institute of Tumor, Guangzhou University of Chinese Medicine, Guangzhou, China.
  • Li XS; Department of Oncology, Lingnan Medical Research Center of Guangzhou University of Chinese Medicine, Guangzhou, China.
  • Qin BY; Department of Oncology, Guangzhou University of Chinese Medicine, Guangzhou, China.
  • Zhou RS; Department of Oncology, Guangzhou University of Chinese Medicine, Guangzhou, China.
  • Pan HF; Department of Oncology, Lingnan Medical Research Center of Guangzhou University of Chinese Medicine, Guangzhou, China.
  • Zheng DY; Department of Oncology, Institute of Tumor, Guangzhou University of Chinese Medicine, Guangzhou, China.
Front Oncol ; 10: 598464, 2020.
Article en En | MEDLINE | ID: mdl-33614486
ABSTRACT
Circular RNAs (circRNAs) are stable covalently closed non-coding RNAs (ncRNAs). Many studies indicate that circRNAs are involved in the pathological and physiological processes of liver cancer. However, the functions of circRNAs in liver cancer immunity are less known. In this review, we summarized the functions of circRNAs in liver cancer, including proliferative, metastasis and apoptosis, liver cancer stemness, cell cycle, immune evasion, glycolysis, angiogenesis, drug resistance/sensitizer, and senescence. Immune escape is considered to be one of the hallmarks of cancer development, and circRNA participates in the immune escape of liver cancer cells by regulating natural killer (NK) cell function. CircRNAs may provide new ideas for immunotherapy in liver cancer.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Front Oncol Año: 2020 Tipo del documento: Article País de afiliación: China
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Front Oncol Año: 2020 Tipo del documento: Article País de afiliación: China