Your browser doesn't support javascript.
loading
Genomic insights into the formation of human populations in East Asia.
Wang, Chuan-Chao; Yeh, Hui-Yuan; Popov, Alexander N; Zhang, Hu-Qin; Matsumura, Hirofumi; Sirak, Kendra; Cheronet, Olivia; Kovalev, Alexey; Rohland, Nadin; Kim, Alexander M; Mallick, Swapan; Bernardos, Rebecca; Tumen, Dashtseveg; Zhao, Jing; Liu, Yi-Chang; Liu, Jiun-Yu; Mah, Matthew; Wang, Ke; Zhang, Zhao; Adamski, Nicole; Broomandkhoshbacht, Nasreen; Callan, Kimberly; Candilio, Francesca; Carlson, Kellie Sara Duffett; Culleton, Brendan J; Eccles, Laurie; Freilich, Suzanne; Keating, Denise; Lawson, Ann Marie; Mandl, Kirsten; Michel, Megan; Oppenheimer, Jonas; Özdogan, Kadir Toykan; Stewardson, Kristin; Wen, Shaoqing; Yan, Shi; Zalzala, Fatma; Chuang, Richard; Huang, Ching-Jung; Looh, Hana; Shiung, Chung-Ching; Nikitin, Yuri G; Tabarev, Andrei V; Tishkin, Alexey A; Lin, Song; Sun, Zhou-Yong; Wu, Xiao-Ming; Yang, Tie-Lin; Hu, Xi; Chen, Liang.
Afiliación
  • Wang CC; Department of Anthropology and Ethnology, Institute of Anthropology, State Key Laboratory of Cellular Stress Biology, School of Life Sciences, Xiamen University, Xiamen, China. wang@xmu.edu.cn.
  • Yeh HY; Department of Genetics, Harvard Medical School, Boston, MA, USA. wang@xmu.edu.cn.
  • Popov AN; Department of Archaeogenetics, Max Planck Institute for the Science of Human History, Jena, Germany. wang@xmu.edu.cn.
  • Zhang HQ; MOE Key Laboratory of Contemporary Anthropology, Department of Anthropology and Human Genetics, School of Life Sciences, Fudan University, Shanghai, China. wang@xmu.edu.cn.
  • Matsumura H; School of Humanities, Nanyang Technological University, Nanyang, Singapore.
  • Sirak K; Scientific Museum, Far Eastern Federal University, Vladivostok, Russia.
  • Cheronet O; Key Laboratory of Biomedical Information Engineering of Ministry of Education, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an, China.
  • Kovalev A; School of Health Science, Sapporo Medical University, Sapporo, Japan.
  • Rohland N; Department of Genetics, Harvard Medical School, Boston, MA, USA.
  • Kim AM; Department of Human Evolutionary Biology, Harvard University, Cambridge, MA, USA.
  • Mallick S; Department of Evolutionary Anthropology, University of Vienna, Vienna, Austria.
  • Bernardos R; Institute of Archaeology, Russian Academy of Sciences, Moscow, Russia.
  • Tumen D; Department of Genetics, Harvard Medical School, Boston, MA, USA.
  • Zhao J; Department of Genetics, Harvard Medical School, Boston, MA, USA.
  • Liu YC; Department of Anthropology, Harvard University, Cambridge, MA, USA.
  • Liu JY; Department of Genetics, Harvard Medical School, Boston, MA, USA.
  • Mah M; Department of Human Evolutionary Biology, Harvard University, Cambridge, MA, USA.
  • Wang K; Broad Institute of Harvard and MIT, Cambridge, MA, USA.
  • Zhang Z; Howard Hughes Medical Institute, Harvard Medical School, Boston, MA, USA.
  • Adamski N; Department of Genetics, Harvard Medical School, Boston, MA, USA.
  • Broomandkhoshbacht N; Department of Anthropology and Archaeology, National University of Mongolia, Ulaanbaatar, Mongolia.
  • Callan K; Key Laboratory of Biomedical Information Engineering of Ministry of Education, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an, China.
  • Candilio F; Institute of Archaeology, National Cheng Kung University, Tainan, Taiwan.
  • Carlson KSD; Department of Anthropology, University of Washington, Seattle, WA, USA.
  • Culleton BJ; Department of Genetics, Harvard Medical School, Boston, MA, USA.
  • Eccles L; Broad Institute of Harvard and MIT, Cambridge, MA, USA.
  • Freilich S; Howard Hughes Medical Institute, Harvard Medical School, Boston, MA, USA.
  • Keating D; Department of Archaeogenetics, Max Planck Institute for the Science of Human History, Jena, Germany.
  • Lawson AM; Department of Genetics, Harvard Medical School, Boston, MA, USA.
  • Mandl K; Department of Genetics, Harvard Medical School, Boston, MA, USA.
  • Michel M; Howard Hughes Medical Institute, Harvard Medical School, Boston, MA, USA.
  • Oppenheimer J; Department of Genetics, Harvard Medical School, Boston, MA, USA.
  • Özdogan KT; Howard Hughes Medical Institute, Harvard Medical School, Boston, MA, USA.
  • Stewardson K; Department of Genetics, Harvard Medical School, Boston, MA, USA.
  • Wen S; Howard Hughes Medical Institute, Harvard Medical School, Boston, MA, USA.
  • Yan S; Department of Evolutionary Anthropology, University of Vienna, Vienna, Austria.
  • Zalzala F; Department of Evolutionary Anthropology, University of Vienna, Vienna, Austria.
  • Chuang R; Institutes of Energy and the Environment, The Pennsylvania State University, University Park, PA, USA.
  • Huang CJ; Department of Anthropology, Pennsylvania State University, University Park, PA, USA.
  • Looh H; Department of Evolutionary Anthropology, University of Vienna, Vienna, Austria.
  • Shiung CC; Department of Evolutionary Anthropology, University of Vienna, Vienna, Austria.
  • Nikitin YG; Department of Genetics, Harvard Medical School, Boston, MA, USA.
  • Tabarev AV; Howard Hughes Medical Institute, Harvard Medical School, Boston, MA, USA.
  • Tishkin AA; Department of Evolutionary Anthropology, University of Vienna, Vienna, Austria.
  • Lin S; Department of Genetics, Harvard Medical School, Boston, MA, USA.
  • Sun ZY; Howard Hughes Medical Institute, Harvard Medical School, Boston, MA, USA.
  • Wu XM; Department of Genetics, Harvard Medical School, Boston, MA, USA.
  • Yang TL; Howard Hughes Medical Institute, Harvard Medical School, Boston, MA, USA.
  • Hu X; Department of Evolutionary Anthropology, University of Vienna, Vienna, Austria.
  • Chen L; Department of Genetics, Harvard Medical School, Boston, MA, USA.
Nature ; 591(7850): 413-419, 2021 03.
Article en En | MEDLINE | ID: mdl-33618348
The deep population history of East Asia remains poorly understood owing to a lack of ancient DNA data and sparse sampling of present-day people1,2. Here we report genome-wide data from 166 East Asian individuals dating to between 6000 BC and AD 1000 and 46 present-day groups. Hunter-gatherers from Japan, the Amur River Basin, and people of Neolithic and Iron Age Taiwan and the Tibetan Plateau are linked by a deeply splitting lineage that probably reflects a coastal migration during the Late Pleistocene epoch. We also follow expansions during the subsequent Holocene epoch from four regions. First, hunter-gatherers from Mongolia and the Amur River Basin have ancestry shared by individuals who speak Mongolic and Tungusic languages, but do not carry ancestry characteristic of farmers from the West Liao River region (around 3000 BC), which contradicts theories that the expansion of these farmers spread the Mongolic and Tungusic proto-languages. Second, farmers from the Yellow River Basin (around 3000 BC) probably spread Sino-Tibetan languages, as their ancestry dispersed both to Tibet-where it forms approximately 84% of the gene pool in some groups-and to the Central Plain, where it has contributed around 59-84% to modern Han Chinese groups. Third, people from Taiwan from around 1300 BC to AD 800 derived approximately 75% of their ancestry from a lineage that is widespread in modern individuals who speak Austronesian, Tai-Kadai and Austroasiatic languages, and that we hypothesize derives from farmers of the Yangtze River Valley. Ancient people from Taiwan also derived about 25% of their ancestry from a northern lineage that is related to, but different from, farmers of the Yellow River Basin, which suggests an additional north-to-south expansion. Fourth, ancestry from Yamnaya Steppe pastoralists arrived in western Mongolia after around 3000 BC but was displaced by previously established lineages even while it persisted in western China, as would be expected if this ancestry was associated with the spread of proto-Tocharian Indo-European languages. Two later gene flows affected western Mongolia: migrants after around 2000 BC with Yamnaya and European farmer ancestry, and episodic influences of later groups with ancestry from Turan.
Asunto(s)

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Genoma Humano / Genómica / Migración Humana Límite: Female / Humans / Male País/Región como asunto: Asia Idioma: En Revista: Nature Año: 2021 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Genoma Humano / Genómica / Migración Humana Límite: Female / Humans / Male País/Región como asunto: Asia Idioma: En Revista: Nature Año: 2021 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido