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PDK4 dictates metabolic resistance to ferroptosis by suppressing pyruvate oxidation and fatty acid synthesis.
Song, Xinxin; Liu, Jiao; Kuang, Feimei; Chen, Xin; Zeh, Herbert J; Kang, Rui; Kroemer, Guido; Xie, Yangchun; Tang, Daolin.
Afiliación
  • Song X; Department of Surgery, UT Southwestern Medical Center, Dallas, TX, USA.
  • Liu J; The Third Affiliated Hospital, Guangzhou Medical University, Guangdong, China.
  • Kuang F; The Third Affiliated Hospital, Guangzhou Medical University, Guangdong, China.
  • Chen X; Department of Surgery, UT Southwestern Medical Center, Dallas, TX, USA.
  • Zeh HJ; Department of Surgery, UT Southwestern Medical Center, Dallas, TX, USA.
  • Kang R; Department of Surgery, UT Southwestern Medical Center, Dallas, TX, USA.
  • Kroemer G; Université Paris Descartes, Sorbonne Paris Cité, 75006 Paris, France; Equipe 11 labellisée Ligue Nationale contre le Cancer, Centre de Recherche des Cordeliers, 75006 Paris, France; Institut National de la Santé et de la Recherche Médicale, U1138, Paris, France; Université Pierre et Marie Curie, 750
  • Xie Y; Department of Oncology, The Second Xiangya Hospital, Central South University, Hunan, China. Electronic address: xieyangchun88@csu.edu.cn.
  • Tang D; Department of Surgery, UT Southwestern Medical Center, Dallas, TX, USA. Electronic address: daolin.tang@utsouthwestern.edu.
Cell Rep ; 34(8): 108767, 2021 02 23.
Article en En | MEDLINE | ID: mdl-33626342
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Pancreáticas / Ácido Pirúvico / Carcinoma Ductal Pancreático / Metabolismo Energético / Ácidos Grasos / Ferroptosis / Piruvato Deshidrogenasa Quinasa Acetil-Transferidora Tipo de estudio: Prognostic_studies Límite: Animals / Humans / Male Idioma: En Revista: Cell Rep Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Pancreáticas / Ácido Pirúvico / Carcinoma Ductal Pancreático / Metabolismo Energético / Ácidos Grasos / Ferroptosis / Piruvato Deshidrogenasa Quinasa Acetil-Transferidora Tipo de estudio: Prognostic_studies Límite: Animals / Humans / Male Idioma: En Revista: Cell Rep Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos