Dendrimers: A New Race of Pharmaceutical Nanocarriers.
Biomed Res Int
; 2021: 8844030, 2021.
Article
en En
| MEDLINE
| ID: mdl-33644232
ABSTRACT
Dendrimers are nanosized, symmetrical molecules in which a small atom or group of atoms is surrounded by the symmetric branches known as dendrons. The structure of dendrimers possesses the greatest impact on their physical and chemical properties. They grow outwards from the core-shell which further reacts with monomers having one reactive or two dormant molecules. Dendrimers' unique characteristics such as hyperbranching, well-defined spherical structure, and high compatibility with the biological systems are responsible for their wide range of applications including medical and biomedical areas. Particularly, the dendrimers' three-dimensional structure can incorporate a wide variety of drugs to form biologically active drug conjugates. In this review, we focus on the synthesis, mechanism of drug encapsulations in dendrimers, and their wide applications in drug delivery.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Portadores de Fármacos
/
Nanoestructuras
/
Dendrímeros
Aspecto:
Determinantes_sociais_saude
Límite:
Humans
Idioma:
En
Revista:
Biomed Res Int
Año:
2021
Tipo del documento:
Article
País de afiliación:
India