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How to make a better T cell: in vivo CRISPR screens have some answers.
Villa, Matteo; Stanczak, Michal A; Pearce, Erika L.
Afiliación
  • Villa M; Department of Immunometabolism, Max Planck Institute of Immunobiology and Epigenetics, 79108 Freiburg, Germany.
  • Stanczak MA; Department of Immunometabolism, Max Planck Institute of Immunobiology and Epigenetics, 79108 Freiburg, Germany.
  • Pearce EL; Department of Immunometabolism, Max Planck Institute of Immunobiology and Epigenetics, 79108 Freiburg, Germany; The Bloomberg-Kimmel Institute for Cancer Immunotherapy at Johns Hopkins, Baltimore, MD 21287, USA. Electronic address: epearce6@jhmi.edu.
Cell ; 184(5): 1135-1136, 2021 03 04.
Article en En | MEDLINE | ID: mdl-33667366
ABSTRACT
Understanding what regulates CD8+ T cell responses is key to effectively harnessing these cells in human disease. In this issue of Cell, Huang et al. and Chen et al. use in vivo CRISPR screens to discover novel regulators of CD8+ T cell immunity to engineer a more efficacious response against cancer and infections.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Repeticiones Palindrómicas Cortas Agrupadas y Regularmente Espaciadas / Neoplasias Límite: Humans Idioma: En Revista: Cell Año: 2021 Tipo del documento: Article País de afiliación: Alemania
Texto completo
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Imprimir
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Repeticiones Palindrómicas Cortas Agrupadas y Regularmente Espaciadas / Neoplasias Límite: Humans Idioma: En Revista: Cell Año: 2021 Tipo del documento: Article País de afiliación: Alemania