Crosstalk of low density lipoprotein and liposome as a paradigm for targeting of 5-fluorouracil into hepatic cells: cytotoxicity and liver deposition.

Alanazi, Saleh A; Harisa, Gamaleldin I; Badran, Mohamed M; Alanazi, Fars K; Elzayat, Ehab; Alomrani, Abdullah H; Al Meanazel, Osaid T; Al Meanazel, Ahmed T

Alanazi, Saleh A; Harisa, Gamaleldin I; Badran, Mohamed M; Alanazi, Fars K; Elzayat, Ehab; Alomrani, Abdullah H; Al Meanazel, Osaid T; Al Meanazel, Ahmed T.

Afiliación

Alanazi SA; Kayyali Chair for Pharmaceutical Industries, Department of Pharmaceutics, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.
Harisa GI; Pharmaceutical Care Services, King Abdulaziz Medical City, Ministry of National Guard Health Affairs, Riyadh, Saudi Arabia.
Badran MM; Kayyali Chair for Pharmaceutical Industries, Department of Pharmaceutics, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.
Alanazi FK; Department of Pharmaceutics, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.
Elzayat E; Department of Biochemistry, College of Pharmacy, Al-Azhar University, Nasr City, Cairo, Egypt.
Alomrani AH; Department of Pharmaceutics, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.
Al Meanazel OT; Department of Pharmaceutics, College of Pharmacy, Al-Azhar University, Nasr City Cairo, Egypt.
Al Meanazel AT; Kayyali Chair for Pharmaceutical Industries, Department of Pharmaceutics, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.

Bioengineered ; 12(1): 914-926, 2021 12.

Article en En | MEDLINE | ID: mdl-33678142

Asunto(s)

Supervivencia Celular/efectos de los fármacos; Fluorouracilo; Lipoproteínas LDL; Liposomas; Hígado/metabolismo; Animales; Carcinoma Hepatocelular/metabolismo; Sistemas de Liberación de Medicamentos/métodos; Fluorouracilo/química; Fluorouracilo/metabolismo; Fluorouracilo/farmacología; Células Hep G2; Hepatocitos/efectos de los fármacos; Hepatocitos/metabolismo; Humanos; Lipoproteínas LDL/química; Lipoproteínas LDL/metabolismo; Liposomas/química; Liposomas/metabolismo; Neoplasias Hepáticas/metabolismo; Masculino; Ratas; Ratas Wistar

Palabras clave

5-FUC; 5-fluorouracil; LDL; cytotoxicity; liposomes; liver targeting

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Supervivencia Celular / Fluorouracilo / Lipoproteínas LDL / Liposomas / Hígado Límite: Animals / Humans / Male Idioma: En Revista: Bioengineered Año: 2021 Tipo del documento: Article País de afiliación: Arabia Saudita Pais de publicación: Estados Unidos

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