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Proton therapy: A therapeutic opportunity for aggressive pediatric meningioma.
Rombi, Barbara; Ruggi, Alessandro; Sardi, Iacopo; Zucchelli, Mino; Scagnet, Mirko; Toni, Francesco; Cammelli, Silvia; Giulietti, Giulia; Fabbri, Viscardo Paolo; Gianno, Francesca; Amichetti, Maurizio; Yock, Torunn Ingrid; Morganti, Alessio Giuseppe; Pession, Andrea; Melchionda, Fraia.
Afiliación
  • Rombi B; Proton Therapy Center, Santa Chiara Hospital, Trento, Italy.
  • Ruggi A; Radiation Oncology Center, Department of Experimental, Diagnostic and Specialty Medicine, DIMES, University of Bologna, Bologna, Italy.
  • Sardi I; Department of Pediatrics, University of Bologna, Bologna, Italy.
  • Zucchelli M; Pediatric Neuro-Oncology Unit, Meyer Children's Hospital, Florence, Italy.
  • Scagnet M; Pediatric Neurosurgery, Institute of Neurological Science, IRCCS Bellaria Hospital, Bologna, Italy.
  • Toni F; Department of Neurosurgery, Meyer Children's Hospital, Florence, Italy.
  • Cammelli S; Pediatric Neuroradiology of Institute of Neurological Science, IRCCS Bellaria Hospital, Bologna, Italy.
  • Giulietti G; Radiation Oncology Center, Department of Experimental, Diagnostic and Specialty Medicine, DIMES, University of Bologna, Bologna, Italy.
  • Fabbri VP; Department of Pediatrics, University of Bologna, Bologna, Italy.
  • Gianno F; Department of Biomedical and Neuromotor Sciences, Pathology Department, University of Bologna, IRCCS Bellaria Hospital, Bologna, Italy.
  • Amichetti M; Department of Radiological, Oncological and Anatomo-Pathological Sciences, Sapienza University of Rome, Rome, Italy.
  • Yock TI; Proton Therapy Center, Santa Chiara Hospital, Trento, Italy.
  • Morganti AG; Pediatric Radiation Oncology Department, Massachusetts General Hospital, Boston, Massachusetts, USA.
  • Pession A; Radiation Oncology Center, Department of Experimental, Diagnostic and Specialty Medicine, DIMES, University of Bologna, Bologna, Italy.
  • Melchionda F; Department of Pediatrics, University of Bologna, Bologna, Italy.
Pediatr Blood Cancer ; 68(5): e28919, 2021 05.
Article en En | MEDLINE | ID: mdl-33682333
ABSTRACT
Meningiomas are an extremely rare histology among pediatric brain tumors, and there is a shortage of literature on their management. Proton therapy is currently used safely and effectively for many types of both pediatric and adult cancer, and its main advantage is the sparing of healthy tissues from radiation, which could translate in the reduction of late side effects. We review the literature on radiotherapy and proton therapy for pediatric meningiomas and report clinical outcomes for two aggressive pediatric meningiomas we treated with protons. Proton therapy might be a safe and effective therapeutic option for this rare subgroup of tumors.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Terapia de Protones / Neoplasias Meníngeas / Meningioma Límite: Child / Humans / Infant / Male Idioma: En Revista: Pediatr Blood Cancer Asunto de la revista: HEMATOLOGIA / NEOPLASIAS / PEDIATRIA Año: 2021 Tipo del documento: Article País de afiliación: Italia

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Terapia de Protones / Neoplasias Meníngeas / Meningioma Límite: Child / Humans / Infant / Male Idioma: En Revista: Pediatr Blood Cancer Asunto de la revista: HEMATOLOGIA / NEOPLASIAS / PEDIATRIA Año: 2021 Tipo del documento: Article País de afiliación: Italia