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Endogenous modification of the chemoattractant CXCL5 alters receptor usage and enhances its activity toward neutrophils and monocytes.
Metzemaekers, Mieke; Mortier, Anneleen; Vacchini, Alessandro; Boff, Daiane; Yu, Karen; Janssens, Rik; Farina, Floriana M; Milanesi, Samantha; Berghmans, Nele; Pörtner, Noëmie; Van Damme, Jo; Allegretti, Marcello; Teixeira, Mauro M; Locati, Massimo; Borroni, Elena M; Amaral, Flavio A; Proost, Paul.
Afiliación
  • Metzemaekers M; Laboratory of Molecular Immunology, Department of Microbiology, Immunology and Transplantation, Rega Institute for Medical Research, KU Leuven, Herestraat 49 box 1042, Leuven B-3000, Belgium.
  • Mortier A; Humanitas Clinical and Research Center, IRCCS, via Manzoni 56, 20089 Rozzano, Milan, Italy.
  • Vacchini A; Laboratory of Molecular Immunology, Department of Microbiology, Immunology and Transplantation, Rega Institute for Medical Research, KU Leuven, Herestraat 49 box 1042, Leuven B-3000, Belgium.
  • Boff D; Humanitas Clinical and Research Center, IRCCS, via Manzoni 56, 20089 Rozzano, Milan, Italy.
  • Yu K; Department of Medical Biotechnologies and Translational Medicine, University of Milan, Via Fratelli Cervi 93, I-20090 Segrate, Italy.
  • Janssens R; Laboratory of Molecular Immunology, Department of Microbiology, Immunology and Transplantation, Rega Institute for Medical Research, KU Leuven, Herestraat 49 box 1042, Leuven B-3000, Belgium.
  • Farina FM; Imunofarmacologia, Departamento de Bioquímica e Imunologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Av Antonio Carlos 6627, Pampulha, Belo Horizonte, Minas Gerais 31270-901, Brasil.
  • Milanesi S; Laboratory of Molecular Immunology, Department of Microbiology, Immunology and Transplantation, Rega Institute for Medical Research, KU Leuven, Herestraat 49 box 1042, Leuven B-3000, Belgium.
  • Berghmans N; Laboratory of Molecular Immunology, Department of Microbiology, Immunology and Transplantation, Rega Institute for Medical Research, KU Leuven, Herestraat 49 box 1042, Leuven B-3000, Belgium.
  • Pörtner N; Imunofarmacologia, Departamento de Bioquímica e Imunologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Av Antonio Carlos 6627, Pampulha, Belo Horizonte, Minas Gerais 31270-901, Brasil.
  • Van Damme J; Humanitas Clinical and Research Center, IRCCS, via Manzoni 56, 20089 Rozzano, Milan, Italy.
  • Allegretti M; Humanitas Clinical and Research Center, IRCCS, via Manzoni 56, 20089 Rozzano, Milan, Italy.
  • Teixeira MM; Department of Medical Biotechnologies and Translational Medicine, University of Milan, Via Fratelli Cervi 93, I-20090 Segrate, Italy.
  • Locati M; Laboratory of Molecular Immunology, Department of Microbiology, Immunology and Transplantation, Rega Institute for Medical Research, KU Leuven, Herestraat 49 box 1042, Leuven B-3000, Belgium.
  • Borroni EM; Laboratory of Molecular Immunology, Department of Microbiology, Immunology and Transplantation, Rega Institute for Medical Research, KU Leuven, Herestraat 49 box 1042, Leuven B-3000, Belgium.
  • Amaral FA; Laboratory of Molecular Immunology, Department of Microbiology, Immunology and Transplantation, Rega Institute for Medical Research, KU Leuven, Herestraat 49 box 1042, Leuven B-3000, Belgium.
  • Proost P; Dompé Farmaceutici SpA, L'Aquila, Italy.
Sci Signal ; 14(673)2021 03 09.
Article en En | MEDLINE | ID: mdl-33688078
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Monocitos / Quimiocina CXCL5 / Neutrófilos Límite: Animals / Humans Idioma: En Revista: Sci Signal Asunto de la revista: CIENCIA / FISIOLOGIA Año: 2021 Tipo del documento: Article País de afiliación: Bélgica Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Monocitos / Quimiocina CXCL5 / Neutrófilos Límite: Animals / Humans Idioma: En Revista: Sci Signal Asunto de la revista: CIENCIA / FISIOLOGIA Año: 2021 Tipo del documento: Article País de afiliación: Bélgica Pais de publicación: Estados Unidos