Role of tumor endothelial marker 1 (Endosialin/CD248) lectin-like domain in lipopolysaccharide-induced macrophage activation and sepsis in mice.

Cheng, Tsung-Lin; Lin, Yu-Syuan; Hong, Yi-Kai; Ma, Chih-Yuan; Tsai, Hung-Wen; Shi, Guey-Yueh; Wu, Hua-Lin; Lai, Chao-Han

Cheng, Tsung-Lin; Lin, Yu-Syuan; Hong, Yi-Kai; Ma, Chih-Yuan; Tsai, Hung-Wen; Shi, Guey-Yueh; Wu, Hua-Lin; Lai, Chao-Han.

Afiliación

Cheng TL; Department of Physiology, School of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan; Orthopedic Research Center, College of Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan; Regenerative Medicine and Cell Therapy Research
Lin YS; Department of Biochemistry and Molecular Biology, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Hong YK; Department of Dermatology, National Cheng Kung University hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan; International Center for Wound Repair and Regeneration, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Ma CY; Department of Biochemistry and Molecular Biology, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Tsai HW; Department of Pathology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Shi GY; Department of Biochemistry and Molecular Biology, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Wu HL; Department of Biochemistry and Molecular Biology, College of Medicine, National Cheng Kung University, Tainan, Taiwan; International Center for Wound Repair and Regeneration, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Lai CH; Department of Biochemistry and Molecular Biology, College of Medicine, National Cheng Kung University, Tainan, Taiwan; Department of Surgery, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan; Department of Biostatistics, Vanderbilt Universi

Transl Res ; 232: 150-162, 2021 06.

Article en En | MEDLINE | ID: mdl-33737161

Asunto(s)

Antígenos CD/fisiología; Lectinas/química; Lipopolisacáridos/farmacología; Activación de Macrófagos/efectos de los fármacos; Proteínas de Neoplasias/fisiología; Sepsis/etiología; Animales; Antígenos CD/química; Antígenos CD/genética; Antígenos de Neoplasias/genética; Eliminación de Gen; Humanos; Inflamación/inducido químicamente; Lipopolisacáridos/metabolismo; Activación de Macrófagos/fisiología; Macrófagos/metabolismo; Ratones; Ratones Endogámicos C57BL; Ratones Noqueados; Ratones Transgénicos; Proteínas de Neoplasias/química; Proteínas Recombinantes/genética; Sepsis/fisiopatología

Palabras clave

ELISAâ¯=â¯enzyme-linked immunosorbent assay; ERKâ¯=â¯extracellular signal-regulated kinase; H&Eâ¯=â¯hematoxylin and eosin; HPFâ¯=â¯high-power field; IL-6â¯=â¯interleukin-6; IκB-αâ¯=â¯nuclear factor-κB inhibitor α; LPSâ¯=â¯lipopolysaccharide; MAPKâ¯=â¯mitogen-activated protein kinase; MPOâ¯=â¯myeloperoxidase; NF-κBâ¯=â¯nuclear factor-κB; PAMPsâ¯=â¯pathogen-associated molecular pattern molecules; PBSâ¯=â¯phosphate-buffered saline; PCRâ¯=â¯polymerase chain reaction; TEM1D1â¯=â¯TEM1 lectin-like domain; TEM1â¯=â¯tumor endothelial marker 1; TLRâ¯=â¯toll-like receptor; TNF-αâ¯=â¯tumor necrosis factor-α; rTEM1D1â¯=â¯recombinant TEM1 lectin-like domain protein

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Antígenos CD / Lipopolisacáridos / Sepsis / Lectinas / Activación de Macrófagos / Proteínas de Neoplasias Límite: Animals / Humans Idioma: En Revista: Transl Res Asunto de la revista: MEDICINA / TECNICAS E PROCEDIMENTOS DE LABORATORIO Año: 2021 Tipo del documento: Article

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