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Roux-en-Y gastric bypass contributes to weight loss-independent improvement in hypothalamic inflammation and leptin sensitivity through gut-microglia-neuron-crosstalk.
Chen, Jiesi; Haase, Nadine; Haange, Sven-Bastiaan; Sucher, Robert; Münzker, Julia; Jäger, Elisabeth; Schischke, Kristin; Seyfried, Florian; von Bergen, Martin; Hankir, Mohammed K; Krügel, Ute; Fenske, Wiebke K.
Afiliación
  • Chen J; Medical Department III, Endocrinology, Nephrology, and Rheumatology, University Hospital of Leipzig, Leipzig, Germany.
  • Haase N; Medical Department III, Endocrinology, Nephrology, and Rheumatology, University Hospital of Leipzig, Leipzig, Germany.
  • Haange SB; Department of Molecular Systems Biology, Helmholtz Center for Environmental Research-UFZ, Permoserstraße 15, 04318 Leipzig, Germany.
  • Sucher R; Division of Bariatric Surgery, Clinic of Visceral, Transplant, Thoracic, and Vascular Surgery, University Hospital, Liebigstraße 20, D-4015, Leipzig, Germany.
  • Münzker J; Medical Department III, Endocrinology, Nephrology, and Rheumatology, University Hospital of Leipzig, Leipzig, Germany.
  • Jäger E; Medical Department III, Endocrinology, Nephrology, and Rheumatology, University Hospital of Leipzig, Leipzig, Germany.
  • Schischke K; Medical Department III, Endocrinology, Nephrology, and Rheumatology, University Hospital of Leipzig, Leipzig, Germany.
  • Seyfried F; Department of General, Visceral, Transplant, Vascular, and Pediatric Surgery, University Hospital, Würzburg, Germany.
  • von Bergen M; Department of Molecular Systems Biology, Helmholtz Center for Environmental Research-UFZ, Permoserstraße 15, 04318 Leipzig, Germany; Institute of Biochemistry, Faculty of Life Sciences, University of Leipzig, Talstraße 33, 04103 Leipzig, Germany.
  • Hankir MK; Department of Experimental Surgery, University Hospital Würzburg, 97080 Würzburg, Germany.
  • Krügel U; Rudolf Boehm Institute of Pharmacology and Toxicology, University of Leipzig, Härtelstraße 16-18, 04107 Leipzig, Germany.
  • Fenske WK; Medical Department III, Endocrinology, Nephrology, and Rheumatology, University Hospital of Leipzig, Leipzig, Germany; Division of Endocrinology, Diabetes, and Metabolism, Medical Department I, University Hospital of Bonn, Bonn, Germany. Electronic address: Wiebke.Fenske@ukbonn.de.
Mol Metab ; 48: 101214, 2021 06.
Article en En | MEDLINE | ID: mdl-33741533
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Obesidad Mórbida / Derivación Gástrica / Transducción de Señal / Pérdida de Peso / Microglía / Leptina / Microbioma Gastrointestinal / Hipotálamo / Neuronas Tipo de estudio: Diagnostic_studies / Etiology_studies / Prognostic_studies Límite: Animals Idioma: En Revista: Mol Metab Año: 2021 Tipo del documento: Article País de afiliación: Alemania Pais de publicación: Alemania
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Obesidad Mórbida / Derivación Gástrica / Transducción de Señal / Pérdida de Peso / Microglía / Leptina / Microbioma Gastrointestinal / Hipotálamo / Neuronas Tipo de estudio: Diagnostic_studies / Etiology_studies / Prognostic_studies Límite: Animals Idioma: En Revista: Mol Metab Año: 2021 Tipo del documento: Article País de afiliación: Alemania Pais de publicación: Alemania