Mechanisms, diagnosis, prevention and management of perioperative opioid-induced hyperalgesia.
Pain Manag
; 11(4): 405-417, 2021 Apr.
Article
en En
| MEDLINE
| ID: mdl-33779215
Lay abstract Opioid-induced hyperalgesia (OIH) occurs when opioid medications worsen rather than decrease pain. We present an educational review of the disorder. Although mechanisms of OIH are thought to primarily start in the brain or brainstem before traveling through the spinal cord to the area of pain in the body, there are likely many causes. We provide a suggested clinical definition and a pathway for clinical differentiation of OIH from other diagnoses to help with management. Finally, we discuss prevention including patient education and medication management choices. As prevention may serve as the best treatment, patient risk factors for OIH, decreased opioid use, and both medication and non-medication strategies are discussed.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Hiperalgesia
/
Analgésicos Opioides
Tipo de estudio:
Diagnostic_studies
/
Risk_factors_studies
Límite:
Humans
Idioma:
En
Revista:
Pain Manag
Año:
2021
Tipo del documento:
Article
País de afiliación:
Estados Unidos
Pais de publicación:
Reino Unido