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Thiamme2-G, a Novel O-GlcNAcase Inhibitor, Reduces Tau Hyperphosphorylation and Rescues Cognitive Impairment in Mice.
Pan, Danmin; Gu, Jin-Hua; Zhang, Jin; Hu, Yae; Liu, Fei; Iqbal, Khalid; Cekic, Nevena; Vocadlo, David J; Dai, Chun-Ling; Gong, Cheng-Xin.
Afiliación
  • Pan D; Department of Neurochemistry, Inge Grundke-Iqbal Research Floor New York State Institute for Basic Research in Developmental Disabilities, Staten Island, NY, USA.
  • Gu JH; Department of Neurochemistry, Inge Grundke-Iqbal Research Floor New York State Institute for Basic Research in Developmental Disabilities, Staten Island, NY, USA.
  • Zhang J; Department of Neurochemistry, Inge Grundke-Iqbal Research Floor New York State Institute for Basic Research in Developmental Disabilities, Staten Island, NY, USA.
  • Hu Y; Department of Neurochemistry, Inge Grundke-Iqbal Research Floor New York State Institute for Basic Research in Developmental Disabilities, Staten Island, NY, USA.
  • Liu F; Department of Neurochemistry, Inge Grundke-Iqbal Research Floor New York State Institute for Basic Research in Developmental Disabilities, Staten Island, NY, USA.
  • Iqbal K; Department of Neurochemistry, Inge Grundke-Iqbal Research Floor New York State Institute for Basic Research in Developmental Disabilities, Staten Island, NY, USA.
  • Cekic N; Department of Chemistry, Simon Fraser University, Burnaby, British Columbia, Canada.
  • Vocadlo DJ; Department of Chemistry, Simon Fraser University, Burnaby, British Columbia, Canada.
  • Dai CL; Department of Molecular Biology and Biochemistry, Simon Fraser University, Burnaby, British Columbia, Canada.
  • Gong CX; Department of Neurochemistry, Inge Grundke-Iqbal Research Floor New York State Institute for Basic Research in Developmental Disabilities, Staten Island, NY, USA.
J Alzheimers Dis ; 81(1): 273-286, 2021.
Article en En | MEDLINE | ID: mdl-33814439
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Beta-N-Acetilhexosaminidasas / Proteínas tau / Inhibidores Enzimáticos / Disfunción Cognitiva Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: J Alzheimers Dis Asunto de la revista: GERIATRIA / NEUROLOGIA Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Países Bajos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Beta-N-Acetilhexosaminidasas / Proteínas tau / Inhibidores Enzimáticos / Disfunción Cognitiva Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: J Alzheimers Dis Asunto de la revista: GERIATRIA / NEUROLOGIA Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Países Bajos