Conjugates of methionine Î³-lyase with polysialic acid: Two approaches to antitumor therapy.

Morozova, E; Anufrieva, N; Koval, V; Lesnova, E; Kushch, A; Timofeeva, V; Solovieva, A; Kulikova, V; Revtovich, S; Demidkina, T

Morozova, E; Anufrieva, N; Koval, V; Lesnova, E; Kushch, A; Timofeeva, V; Solovieva, A; Kulikova, V; Revtovich, S; Demidkina, T.

Afiliación

Morozova E; Engelhardt Institute of Molecular Biology of the Russian Academy of Sciences, 119991 Moscow, Russia. Electronic address: elmorozova@yahoo.com.
Anufrieva N; Engelhardt Institute of Molecular Biology of the Russian Academy of Sciences, 119991 Moscow, Russia.
Koval V; Engelhardt Institute of Molecular Biology of the Russian Academy of Sciences, 119991 Moscow, Russia.
Lesnova E; Gamaleya National Research Center of Epidemiology and Microbiology, Ministry of Health of the Russian Federation, 123098 Moscow, Russia.
Kushch A; Gamaleya National Research Center of Epidemiology and Microbiology, Ministry of Health of the Russian Federation, 123098 Moscow, Russia.
Timofeeva V; N. N. Semenov Institute of Chemical Physics of the Russian Academy of Sciences, 119991 Moscow, Russia.
Solovieva A; N. N. Semenov Institute of Chemical Physics of the Russian Academy of Sciences, 119991 Moscow, Russia.
Kulikova V; Engelhardt Institute of Molecular Biology of the Russian Academy of Sciences, 119991 Moscow, Russia.
Revtovich S; Engelhardt Institute of Molecular Biology of the Russian Academy of Sciences, 119991 Moscow, Russia.
Demidkina T; Engelhardt Institute of Molecular Biology of the Russian Academy of Sciences, 119991 Moscow, Russia.

Int J Biol Macromol ; 182: 394-401, 2021 Jul 01.

Article en En | MEDLINE | ID: mdl-33839182

Asunto(s)

Antineoplásicos/farmacología; Liasas de Carbono-Azufre/química; Neoplasias/tratamiento farmacológico; Ácidos Siálicos/química; Animales; Antineoplásicos/uso terapéutico; Liasas de Carbono-Azufre/metabolismo; Liasas de Carbono-Azufre/farmacocinética; Liasas de Carbono-Azufre/farmacología; Línea Celular Tumoral; Femenino; Humanos; Cinética; Células MCF-7; Ratones; Ratones Endogámicos BALB C; Neoplasias/terapia; Ácidos Siálicos/farmacología; Ácidos Siálicos/uso terapéutico

Palabras clave

Cytotoxic activity; Methionine Î³-lyase; Polysyalic acid conjugates; S-(allyl/alkyl)-L-cysteine sulfoxides; Thiosulfinates produced in situ by pharmacological pair

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Ácidos Siálicos / Liasas de Carbono-Azufre / Neoplasias / Antineoplásicos Límite: Animals / Female / Humans Idioma: En Revista: Int J Biol Macromol Año: 2021 Tipo del documento: Article

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