Development of DNA-compatible hydroxycarbonylation reactions using chloroform as a source of carbon monoxide.
Bioorg Med Chem
; 38: 116118, 2021 05 15.
Article
en En
| MEDLINE
| ID: mdl-33839592
ABSTRACT
A robust palladium-catalyzed hydroxycarbonylation of aryl halides on DNA has been developed. Instead of Mo(CO)6 as a source of carbon monoxide as previously described in the literature, chloroform was used as a surrogate in this report for the purpose of avoiding to use a large excess of molybdenum reagent which is not totally soluble in aqueous reaction mixtures.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
ADN
/
Monóxido de Carbono
/
Cloroformo
Idioma:
En
Revista:
Bioorg Med Chem
Asunto de la revista:
BIOQUIMICA
/
QUIMICA
Año:
2021
Tipo del documento:
Article