Serious bronchospasm induced by cisatracurium besylate: A case report.
Medicine (Baltimore)
; 100(15): e25516, 2021 Apr 16.
Article
en En
| MEDLINE
| ID: mdl-33847670
ABSTRACT
RATIONALE Cis-atracurium as an intermediate-acting non-depolarizing neuromuscular blocker is widely used clinically with less causing cyclic fluctuations and less histamine release. As the use rate increases, allergic reactions and anaphylactoid reactions caused by cis-atracurium increase. PATIENT CONCERNS A 23-year-old woman underwent laparoscopic bariatric surgery. Airway spasm occurred after anesthesia induction and the operation was suspended. After adjustment, the anesthesia was performed with the same anesthetic scheme again. After induction, skin flushing and airway resistance increased, then the symptoms were relieved. When the cis-atracurium was given again, the symptoms of airway spasm reappeared immediately, and after communicating with the family, the operation was successfully completed with rocuronium. DIAGNOSES Serious bronchospasm induced by cisatracurium besylate. INTERVENTIONS:
The patient was undergone assisted ventilation with continuous positive airway pressure (CPAP) and aminophylline 250âmg, methylprednisolone 80âmg were given intravenously.OUTCOMES:
There was no any obvious discomfort in the patient's self-report during the next day's visit. The patient was discharged 7âdays later. No abnormalities were observed during following 4âweeks. LESSONS Although the anaphylactoid reactions caused by cis-atracurium are rare, the bronchospasm and anaphylactic shock caused by it greatly increase the risk of anesthesia, which should be taken seriously by clinicians. Increased vigilance in diagnosis, and treatment are essential to prevent aggravation and further complication.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Atracurio
/
Espasmo Bronquial
/
Anafilaxia
/
Anestesia General
/
Bloqueantes Neuromusculares
Límite:
Adult
/
Female
/
Humans
Idioma:
En
Revista:
Medicine (Baltimore)
Año:
2021
Tipo del documento:
Article
País de afiliación:
China