Case Report: Maintenance of Desensitization to Nebulized Colomycin Over 10 Years.
Front Pediatr
; 9: 663228, 2021.
Article
en En
| MEDLINE
| ID: mdl-33869120
ABSTRACT
Drug desensitization can be achieved successfully by gradual drug dose increases in different protocols. Most protocols are designed to obtain temporal tolerance. The data on long-term maintenance of drug tolerance is scarce. Based on an IgE-mediated colomycin allergy we describe the maintenance of drug tolerance to nebulized drug for the period of 10 years in a 15-year-old cystic fibrosis patient, proceeded by successful rush intravenous desensitization protocol. The mechanism of drug tolerance is largely speculative; however, long-term maintenance of it seems achievable by continuous local drug application.
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1
Colección:
01-internacional
Base de datos:
MEDLINE
Idioma:
En
Revista:
Front Pediatr
Año:
2021
Tipo del documento:
Article
País de afiliación:
Austria