CD45RA-CD25highCD127-CD4+ activated regulatory T cells are correlated with de novo donor-specific anti-HLA antibody formation after kidney transplantation in standard immunosuppression.

Tomita, Yusuke; Ishida, Hiroaki; Uehara, Saeko; Takiguchi, Shinya; Sato, Takehito; Nakamura, Michio

CD45RA^-CD25^highCD127^-CD4⁺ activated regulatory T cells are correlated with de novo donor-specific anti-HLA antibody formation after kidney transplantation in standard immunosuppression.

Tomita, Yusuke; Ishida, Hiroaki; Uehara, Saeko; Takiguchi, Shinya; Sato, Takehito; Nakamura, Michio.

Afiliación

Tomita Y; Department of Transplant Surgery, Tokai University School of Medicine, Kanagawa, Japan. Electronic address: ytomita@tokai.ac.jp.
Ishida H; Department of Transplant Surgery, Tokai University School of Medicine, Kanagawa, Japan.
Uehara S; Department of Transplant Surgery, Tokai University School of Medicine, Kanagawa, Japan.
Takiguchi S; Department of Transplant Surgery, Tokai University School of Medicine, Kanagawa, Japan.
Sato T; Department of Immunology, Tokai University School of Medicine, Kanagawa, Japan.
Nakamura M; Department of Transplant Surgery, Tokai University School of Medicine, Kanagawa, Japan.

Int Immunopharmacol ; 97: 107661, 2021 Aug.

Article en En | MEDLINE | ID: mdl-33887579

Asunto(s)

Rechazo de Injerto/inmunología; Antígenos HLA/inmunología; Isoanticuerpos/metabolismo; Trasplante de Riñón/efectos adversos; Linfocitos T Reguladores/inmunología; Adulto; Femenino; Rechazo de Injerto/sangre; Rechazo de Injerto/epidemiología; Rechazo de Injerto/prevención & control; Humanos; Tolerancia Inmunológica; Inmunosupresores/administración & dosificación; Isoanticuerpos/sangre; Isoanticuerpos/inmunología; Activación de Linfocitos; Masculino; Persona de Mediana Edad; Estudios Retrospectivos; Medición de Riesgo/métodos; Factores de Riesgo; Linfocitos T Reguladores/metabolismo

Palabras clave

Acute rejection; CD45RA(-) activated regulatory T cells; Kidney transplantation; Regulatory T cell subsets; de novo donor-specific anti-human leukocyte antigen antibodies

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Trasplante de Riñón / Linfocitos T Reguladores / Rechazo de Injerto / Antígenos HLA / Isoanticuerpos Tipo de estudio: Etiology_studies / Observational_studies / Risk_factors_studies Límite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: Int Immunopharmacol Asunto de la revista: ALERGIA E IMUNOLOGIA / FARMACOLOGIA Año: 2021 Tipo del documento: Article Pais de publicación: Países Bajos

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