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A soft and transparent contact lens for the wireless quantitative monitoring of intraocular pressure.
Kim, Joohee; Park, Jihun; Park, Young-Geun; Cha, Eunkyung; Ku, Minjae; An, Hyeon Seok; Lee, Kyoung-Pil; Huh, Man-Il; Kim, Junmo; Kim, Taek-Soo; Kim, Dai Woo; Kim, Hong Kyun; Park, Jang-Ung.
Afiliación
  • Kim J; Department of Materials Science and Engineering, Yonsei University, Seoul, Republic of Korea.
  • Park J; Center for Nanomedicine, Institute for Basic Science (IBS), Yonsei University, Seoul, Republic of Korea.
  • Park YG; Department of Materials Science and Engineering, Yonsei University, Seoul, Republic of Korea.
  • Cha E; Center for Nanomedicine, Institute for Basic Science (IBS), Yonsei University, Seoul, Republic of Korea.
  • Ku M; Department of Materials Science and Engineering, Yonsei University, Seoul, Republic of Korea.
  • An HS; Center for Nanomedicine, Institute for Basic Science (IBS), Yonsei University, Seoul, Republic of Korea.
  • Lee KP; School of Materials Science and Engineering, Ulsan National Institute of Science and Technology (UNIST), Ulsan, Republic of Korea.
  • Huh MI; Department of Materials Science and Engineering, Yonsei University, Seoul, Republic of Korea.
  • Kim J; Center for Nanomedicine, Institute for Basic Science (IBS), Yonsei University, Seoul, Republic of Korea.
  • Kim TS; Department of Materials Science and Engineering, Yonsei University, Seoul, Republic of Korea.
  • Kim DW; Center for Nanomedicine, Institute for Basic Science (IBS), Yonsei University, Seoul, Republic of Korea.
  • Kim HK; Department of Materials Science and Engineering, Yonsei University, Seoul, Republic of Korea.
  • Park JU; Center for Nanomedicine, Institute for Basic Science (IBS), Yonsei University, Seoul, Republic of Korea.
Nat Biomed Eng ; 5(7): 772-782, 2021 07.
Article en En | MEDLINE | ID: mdl-33941897
Continuous detection of raised intraocular pressure (IOP) could benefit the monitoring of patients with glaucoma. Current contact lenses with embedded sensors for measuring IOP are rigid, bulky, partially block vision or are insufficiently sensitive. Here, we report the design and testing in volunteers of a soft and transparent contact lens for the quantitative monitoring of IOP in real time using a smartphone. The contact lens incorporates a strain sensor, a wireless antenna, capacitors, resistors, stretchable metal interconnects and an integrated circuit for wireless communication. In rabbits, the lens provided measurements that match those of a commercial tonometer. In ten human participants, the lens proved to be safe, and reliably provided accurate quantitative measurements of IOP without inducing inflammation.
Asunto(s)

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Presión Intraocular / Monitoreo Fisiológico Límite: Adult / Animals / Female / Humans Idioma: En Revista: Nat Biomed Eng Año: 2021 Tipo del documento: Article Pais de publicación: Reino Unido

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Presión Intraocular / Monitoreo Fisiológico Límite: Adult / Animals / Female / Humans Idioma: En Revista: Nat Biomed Eng Año: 2021 Tipo del documento: Article Pais de publicación: Reino Unido