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Aconitine induces mitochondrial energy metabolism dysfunction through inhibition of AMPK signaling and interference with mitochondrial dynamics in SH-SY5Y cells.
Yang, Liang; Chen, Yan; Zhou, Jie; Sun, Jiayi; Jiang, Wanyanhan; Liu, Tianyu; Rao, Chaolong; Pan, Xiaoqi.
Afiliación
  • Yang L; School of Pharmacy and School of Public Health, Chengdu University of Traditional Chinese Medicine, Chengdu, 611137, China.
  • Chen Y; School of Pharmacy and School of Public Health, Chengdu University of Traditional Chinese Medicine, Chengdu, 611137, China.
  • Zhou J; School of Pharmacy and School of Public Health, Chengdu University of Traditional Chinese Medicine, Chengdu, 611137, China.
  • Sun J; Innovation Institute of Chinese Medicine and Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, 611137, China.
  • Jiang W; School of Pharmacy and School of Public Health, Chengdu University of Traditional Chinese Medicine, Chengdu, 611137, China.
  • Liu T; School of Sport, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China.
  • Rao C; School of Pharmacy and School of Public Health, Chengdu University of Traditional Chinese Medicine, Chengdu, 611137, China; R&D Center for Efficiency, Safety and Application in Chinese Materia Medica with Medical and Edible Values, School of Public Health, Chengdu University of Traditional Chine
  • Pan X; School of Pharmacy and School of Public Health, Chengdu University of Traditional Chinese Medicine, Chengdu, 611137, China. Electronic address: panxiaoqi1104@cdutcm.edu.cn.
Toxicol Lett ; 347: 36-44, 2021 Sep 01.
Article en En | MEDLINE | ID: mdl-33945864
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Aconitina / Síndromes de Neurotoxicidad / Metabolismo Energético / Proteínas Quinasas Activadas por AMP / Dinámicas Mitocondriales / Mitocondrias / Neuronas Límite: Humans Idioma: En Revista: Toxicol Lett Año: 2021 Tipo del documento: Article País de afiliación: China Pais de publicación: Países Bajos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Aconitina / Síndromes de Neurotoxicidad / Metabolismo Energético / Proteínas Quinasas Activadas por AMP / Dinámicas Mitocondriales / Mitocondrias / Neuronas Límite: Humans Idioma: En Revista: Toxicol Lett Año: 2021 Tipo del documento: Article País de afiliación: China Pais de publicación: Países Bajos