Investigation of the effects of propofol/ketamine versus propofol/fentanyl on nausea- vomiting administered for sedation in children undergoing magnetic resonance imaging: a prospective randomized double-blinded study
Turk J Med Sci
; 51(4): 2120-2126, 2021 08 30.
Article
en En
| MEDLINE
| ID: mdl-33957724
ABSTRACT
Background/aim:
In this study, we aimed to compare the effects of propofol-ketamine and propofol-fentanyl sedations on post- procedure nausea-vomiting in children undergoing magnetic resonance imaging (MRI). Materials andmethods:
This study included 100 pediatric patients (210 years old) who had propofol-ketamine and propofol-fentanyl for sedation to undergo MRI. The patients were divided into two groups, and sedation was performed through propofol-ketamine (Group K; n = 50) or propofol-fentanyl (Group F; n = 50). For sedation induction, intravenous (IV) bolus of 1.2 mg/kg propofol and 1 mg/kg ketamine were administered in Group K, IV bolus of 1.2 mg/kg propofol, and 1 µg/kg fentanyl in Group F. All patients received 0.5 mg/kg IV bolus propofol in additional doses when the Ramsay Sedation Score (RSS) was below 4 for maintenance. Perioperative heart rate, systolic arterial pressure, peripheral oxygen saturation, respiratory rate, and nausea-vomiting scores were recorded for each patient.Results:
There was no difference between the groups in terms of nausea incidences at the 1st hour. However, the rate of vomiting was significantly higher in Group K.Conclusion:
In our study, we showed that the vomiting rate was higher in the 1st hour in Group K compared to Group F.Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Imagen por Resonancia Magnética
/
Propofol
/
Fentanilo
/
Sedación Consciente
/
Náusea y Vómito Posoperatorios
/
Hipnóticos y Sedantes
/
Ketamina
Tipo de estudio:
Clinical_trials
/
Observational_studies
Límite:
Child
/
Child, preschool
/
Female
/
Humans
/
Male
Idioma:
En
Revista:
Turk J Med Sci
Año:
2021
Tipo del documento:
Article
País de afiliación:
Turquía