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Selumetinib normalizes Ras/MAPK signaling in clinically relevant neurofibromatosis type 1 minipig tissues in vivo.
Osum, Sara H; Coutts, Alexander W; Duerre, Dylan J; Tschida, Barbara R; Kirstein, Mark N; Fisher, James; Bell, W Robert; Delpuech, Oona; Smith, Paul D; Widemann, Brigitte C; Moertel, Christopher L; Largaespada, David A; Watson, Adrienne L.
Afiliación
  • Osum SH; Department of Pediatrics, University of Minnesota, Minneapolis, Minnesota, USA.
  • Coutts AW; Recombinetics Inc., Eagan, Minnesota, USA.
  • Duerre DJ; Recombinetics Inc., Eagan, Minnesota, USA.
  • Tschida BR; Recombinetics Inc., Eagan, Minnesota, USA.
  • Kirstein MN; Department of Pediatrics, University of Minnesota, Minneapolis, Minnesota, USA.
  • Fisher J; Department of Experimental and Clinical Pharmacology, University of Minnesota, Minneapolis, Minnesota, USA.
  • Bell WR; Department of Pediatrics, University of Minnesota, Minneapolis, Minnesota, USA.
  • Delpuech O; Department of Experimental and Clinical Pharmacology, University of Minnesota, Minneapolis, Minnesota, USA.
  • Smith PD; Department of Pediatrics, University of Minnesota, Minneapolis, Minnesota, USA.
  • Widemann BC; Division of Neuropathology, Department of Lab Medicine and Pathology, University of Minnesota, Minneapolis, Minnesota, USA.
  • Moertel CL; Oncology R&D, AstraZeneca, Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, UK.
  • Largaespada DA; Oncology R&D, AstraZeneca, Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, UK.
  • Watson AL; Pediatric Oncology Branch, Rare Tumor Initiative, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland, USA.
Neurooncol Adv ; 3(1): vdab020, 2021.
Article en En | MEDLINE | ID: mdl-33978635
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Neurooncol Adv Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Neurooncol Adv Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido