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A proposed "Radiological Evaluation Score for Bone Tumors" (REST): An objective system for assessment of a radiograph in patients with suspected bone tumor.
Salunke, A A; Nandy, K; Puj, K; Kamani, M; Pathak, S; Shah, J; Bhalerao, R H; Jain, A; Sharma, M; Warikoo, V; Patel, K; Rathod, P; Bhatt, S; Tank, T; Pandya, S.
Afiliación
  • Salunke AA; Department of Surgical Oncology, Gujarat Cancer Research Institute (GCRI), Ahmedabad, Gujarat, India. drabhijeetsalunke@gmail.com.
  • Nandy K; Department of Anesthesia, Gujarat Cancer Research Institute (GCRI), Ahmedabad, Gujarat, India.
  • Puj K; Department of Anesthesia, Gujarat Cancer Research Institute (GCRI), Ahmedabad, Gujarat, India.
  • Kamani M; Department of Anesthesia, Gujarat Cancer Research Institute (GCRI), Ahmedabad, Gujarat, India.
  • Pathak S; Department of Orthopedics, MM Institute of Medical Sciences & Research, Ambala, India.
  • Shah J; Osteo Care - Ortho Onco Clinic, Ahmedabad, Gujarat, India.
  • Bhalerao RH; Department of Electrical Engineering and Computer Science, Institute of Infrastructure, Technology, Research And Management, Ahmedabad, Gujarat, India.
  • Jain A; Department of Anesthesia, Gujarat Cancer Research Institute (GCRI), Ahmedabad, Gujarat, India.
  • Sharma M; Department of Anesthesia, Gujarat Cancer Research Institute (GCRI), Ahmedabad, Gujarat, India.
  • Warikoo V; Department of Anesthesia, Gujarat Cancer Research Institute (GCRI), Ahmedabad, Gujarat, India.
  • Patel K; Department of Anesthesia, Gujarat Cancer Research Institute (GCRI), Ahmedabad, Gujarat, India.
  • Rathod P; Department of Anesthesia, Gujarat Cancer Research Institute (GCRI), Ahmedabad, Gujarat, India.
  • Bhatt S; Department of Anesthesia, Gujarat Cancer Research Institute (GCRI), Ahmedabad, Gujarat, India.
  • Tank T; Department of Anesthesia, Gujarat Cancer Research Institute (GCRI), Ahmedabad, Gujarat, India.
  • Pandya S; Department of Anesthesia, Gujarat Cancer Research Institute (GCRI), Ahmedabad, Gujarat, India.
Musculoskelet Surg ; 106(4): 371-382, 2022 Dec.
Article en En | MEDLINE | ID: mdl-33982208
BACKGROUND: Although radiographs have been widely used in the evaluation of patients with suspected bone tumors, the lack of an objective radiological assessment method leads to a challenge in reaching correct diagnosis. The study aimed to propose a Radiological Evaluation Score for Bone Tumors (REST) which includes eight radiological factors [characteristics, content, cortical breach, distinctiveness, distribution, periosteal reaction, fracture, and soft tissue swelling] to form a single score along with its validation by multidisciplinary observers. METHODS: We reviewed the radiographs of 100 patients with a primary bone tumor which were selected at random from the database between January 2017 and January 2019 of a tertiary cancer center. Four reviewers (two orthopedic oncologists and two surgical oncologists) independently assessed the radiographs, based on the reporting system of REST. We constituted two groups according to the probable diagnosis of bone tumor (suspected benign tumor and suspected malignant tumor). RESULTS: The mean score in the suspected benign tumor group was 1.1 (range 0-3, 95% CI 0.8-1.3) and in malignant tumor group was 6.1 (range 2-8, 95% CI 5.8-6.4). A receiver operator characteristic (ROC) curve for REST was with a cutoff of 3.5, with the most diagnostic value area under curve (AUC) of 0.99. The sensitivity was 98% and specificity was 100% with a positive predictive value of 100% and a negative predictive value of 98%. The inter-observer correlation coefficient was 0.985 (p value < 0.05), and Fleiss kappa value for the prediction of the benign or malignant lesion was 0.97 (p value < 0.05). The characteristics and content of tumor, cortical erosion, distinctiveness, distribution, periosteal reaction, and soft tissue mass had a significant correlation with the aggressiveness of bone lesion p value < 0.05. CONCLUSIONS: The Radiological Evaluation Score for Bone Tumors (REST) is a structured reporting and objective method for the assessment of radiographs in patients with suspected bone tumors. This method is a reliable and helpful tool for clinicians in their outdoor patient department to differentiate a radiograph of a suspected benign tumor from a malignant bone tumor.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Óseas Tipo de estudio: Diagnostic_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: Musculoskelet Surg Asunto de la revista: ORTOPEDIA Año: 2022 Tipo del documento: Article País de afiliación: India Pais de publicación: Italia

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Óseas Tipo de estudio: Diagnostic_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: Musculoskelet Surg Asunto de la revista: ORTOPEDIA Año: 2022 Tipo del documento: Article País de afiliación: India Pais de publicación: Italia