<i>LRP1B</i> mutation is associated with tumor HPV status and promotes poor disease outcomes with a higher mutation count in HPV-related cervical carcinoma and head & neck squamous cell carcinoma.

Cao, Can-Hui; Liu, Rang; Lin, Xin-Ran; Luo, Jia-Qi; Cao, Li-Juan; Zhang, Qiu-Ju; Lin, Shou-Ren; Geng, Lan; Sun, Zhong-Yi; Ye, Si-Kang; Yu, Zhi-Ying; Shi, Yu; Xia, Xi

LRP1B mutation is associated with tumor HPV status and promotes poor disease outcomes with a higher mutation count in HPV-related cervical carcinoma and head & neck squamous cell carcinoma.

Cao, Can-Hui; Liu, Rang; Lin, Xin-Ran; Luo, Jia-Qi; Cao, Li-Juan; Zhang, Qiu-Ju; Lin, Shou-Ren; Geng, Lan; Sun, Zhong-Yi; Ye, Si-Kang; Yu, Zhi-Ying; Shi, Yu; Xia, Xi.

Afiliación

Cao CH; Center for Reproductive Medicine, Department of Obstetrics and Gynecology, Peking University Shenzhen Hospital, Shenzhen Peking University-The Hong Kong University of Science and Technology Medical Center, Guangdong, 518036, China.
Liu R; Center for Reproductive Medicine, Department of Obstetrics and Gynecology, Peking University Shenzhen Hospital, Shenzhen Peking University-The Hong Kong University of Science and Technology Medical Center, Guangdong, 518036, China.
Lin XR; Center for Reproductive Medicine, Department of Obstetrics and Gynecology, Peking University Shenzhen Hospital, Shenzhen Peking University-The Hong Kong University of Science and Technology Medical Center, Guangdong, 518036, China.
Luo JQ; Center for Reproductive Medicine, Department of Obstetrics and Gynecology, Peking University Shenzhen Hospital, Shenzhen Peking University-The Hong Kong University of Science and Technology Medical Center, Guangdong, 518036, China.
Cao LJ; Center for Reproductive Medicine, Department of Obstetrics and Gynecology, Peking University Shenzhen Hospital, Shenzhen Peking University-The Hong Kong University of Science and Technology Medical Center, Guangdong, 518036, China.
Zhang QJ; Center for Reproductive Medicine, Department of Obstetrics and Gynecology, Peking University Shenzhen Hospital, Shenzhen Peking University-The Hong Kong University of Science and Technology Medical Center, Guangdong, 518036, China.
Lin SR; Center for Reproductive Medicine, Department of Obstetrics and Gynecology, Peking University Shenzhen Hospital, Shenzhen Peking University-The Hong Kong University of Science and Technology Medical Center, Guangdong, 518036, China.
Geng L; Center for Reproductive Medicine, Department of Obstetrics and Gynecology, Peking University Shenzhen Hospital, Shenzhen Peking University-The Hong Kong University of Science and Technology Medical Center, Guangdong, 518036, China.
Sun ZY; Center for Reproductive Medicine, Department of Obstetrics and Gynecology, Peking University Shenzhen Hospital, Shenzhen Peking University-The Hong Kong University of Science and Technology Medical Center, Guangdong, 518036, China.
Ye SK; Department of Critical Care Medicine, The Eighth Affiliated Hospital, Sun Yat-sen University, Shenzhen, China.
Yu ZY; Department of Gynecology, The First Affiliated Hospital of Shenzhen University, Health Science Center, Shenzhen Second People's Hospital, Shenzhen, Guangdong, China.
Shi Y; Center for Reproductive Medicine, Department of Obstetrics and Gynecology, Peking University Shenzhen Hospital, Shenzhen Peking University-The Hong Kong University of Science and Technology Medical Center, Guangdong, 518036, China.
Xia X; Center for Reproductive Medicine, Department of Obstetrics and Gynecology, Peking University Shenzhen Hospital, Shenzhen Peking University-The Hong Kong University of Science and Technology Medical Center, Guangdong, 518036, China.

Int J Biol Sci ; 17(7): 1744-1756, 2021.

Article en En | MEDLINE | ID: mdl-33994859

Asunto(s)

Neoplasias de Cabeza y Cuello/genética; Mutación; Papillomaviridae; Infecciones por Papillomavirus/genética; Receptores de LDL/genética; Carcinoma de Células Escamosas de Cabeza y Cuello/genética; Neoplasias del Cuello Uterino/genética; Biomarcadores de Tumor/genética; Biomarcadores de Tumor/metabolismo; Variaciones en el Número de Copia de ADN; Análisis Mutacional de ADN; ADN de Neoplasias/genética; ADN de Neoplasias/metabolismo; Femenino; Perfilación de la Expresión Génica; Neoplasias de Cabeza y Cuello/metabolismo; Neoplasias de Cabeza y Cuello/patología; Humanos; Persona de Mediana Edad; Infecciones por Papillomavirus/metabolismo; Infecciones por Papillomavirus/patología; Receptores de LDL/metabolismo; Carcinoma de Células Escamosas de Cabeza y Cuello/metabolismo; Carcinoma de Células Escamosas de Cabeza y Cuello/patología; Neoplasias del Cuello Uterino/metabolismo; Neoplasias del Cuello Uterino/patología

Palabras clave

LRP1B mutation; cervical carcinoma; head and neck squamous cell carcinoma; tumor HPV status; tumor mutation count

Texto completo

Añadir a Mi BVS

Imprimir

XML

PubMed Links

Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Papillomaviridae / Receptores de LDL / Neoplasias del Cuello Uterino / Infecciones por Papillomavirus / Carcinoma de Células Escamosas de Cabeza y Cuello / Neoplasias de Cabeza y Cuello / Mutación Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Female / Humans / Middle aged Idioma: En Revista: Int J Biol Sci Asunto de la revista: BIOLOGIA Año: 2021 Tipo del documento: Article País de afiliación: China Pais de publicación: Australia

Texto completo

Añadir a Mi BVS

Imprimir

XML

PubMed Links

Buscar en Google