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Neuropsychological and executive screening in obstructive sleep apnea: early effect of ventilatory therapy.
Vigorè, Martina; Taurino, Eugenia; Maestroni, Rita; Torlaschi, Valeria; Maffoni, Marina; Maestri, Roberto; Pierobon, Antonia; Fanfulla, Francesco.
Afiliación
  • Vigorè M; Psychology Unit, Istituti Clinici Scientifici Maugeri IRCCS, Institute of Montescano, Montescano, Pavia, Italy.
  • Taurino E; Unit of Respiratory Function and Sleep Medicine, Istituti Clinici Scientifici Maugeri IRCCS, Institute of Montescano, Pavia, Italy.
  • Maestroni R; Unit of Respiratory Function and Sleep Medicine, Istituti Clinici Scientifici Maugeri IRCCS, Institute of Montescano, Pavia, Italy.
  • Torlaschi V; Psychology Unit, Istituti Clinici Scientifici Maugeri IRCCS, Institute of Montescano, Montescano, Pavia, Italy.
  • Maffoni M; Psychology Unit, Istituti Clinici Scientifici Maugeri IRCCS, Institute of Montescano, Montescano, Pavia, Italy.
  • Maestri R; Department of Biomedical Engineering, Istituti Clinici Scientifici Maugeri IRCCS, Institute of Montescano, Pavia, Italy.
  • Pierobon A; Psychology Unit, Istituti Clinici Scientifici Maugeri IRCCS, Institute of Montescano, Montescano, Pavia, Italy - antonia.pierobon@icsmaugeri.it.
  • Fanfulla F; Unit of Respiratory Function and Sleep Medicine, Istituti Clinici Scientifici Maugeri IRCCS, Institute of Montescano, Pavia, Italy.
Minerva Med ; 112(3): 346-353, 2021 Jun.
Article en En | MEDLINE | ID: mdl-34015910
ABSTRACT

BACKGROUND:

Obstructive sleep apnea (OSA) is often associated with clinical, psychological and neuropsychological comorbidities such as Mild Cognitive Impairment (MCI). This study evaluated changes in clinical, psychosocial, Health Related Quality of Life (HRQoL) and neuropsychological profile in OSA subjects after ventilatory therapy, making comparison with normative data. The aim of the study was to verify the suitability of the HRQoL and neuropsychological screening tests in detecting variations in OSA subjects.

METHODS:

At baseline, 32 OSA subjects underwent the following assessment EuroQol (EQ-5D-3L) and EQ VAS, Hospital Anxiety and Depression Scale (HADS), Montreal Cognitive Assessment (MoCA) and Frontal Assessment Battery (FAB). After the ventilatory titration, 31 OSA subjects repeated the EQ VAS, MoCA and FAB assessment.

RESULTS:

The analyzed subjects (77% male, 58.97±10.06 years old and 47.34±26.67 AHI [ev*hr-1]) showed low emotive distress, a lower perception of HRQoL than normative data and 35.48% of them exhibited executive deficits, too. MCI was detected in 3.2% and 48.4% of subjects after normative Italian and international correction, respectively. Subsequently the ventilatory therapy and the rehabilitative interdisciplinary treatment, subjects improved in EQ VAS (68.23±18.73 vs. 87.13±10.80, P=0.0001), FAB scores (15,30±2.03 vs. 16,65±1,40, P=0.007) and MoCA memory subtest scores (2.16±1.34 vs. 3.06±1.63, P=0.008).

CONCLUSIONS:

Ventilatory therapy provided during a rehabilitative and interdisciplinary program increased subjects' HRQoL, executive functions and verbal memory.
Asunto(s)

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Calidad de Vida / Respiración con Presión Positiva / Apnea Obstructiva del Sueño / Disfunción Cognitiva Tipo de estudio: Diagnostic_studies / Etiology_studies / Screening_studies Aspecto: Patient_preference Límite: Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Minerva Med Año: 2021 Tipo del documento: Article País de afiliación: Italia

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Calidad de Vida / Respiración con Presión Positiva / Apnea Obstructiva del Sueño / Disfunción Cognitiva Tipo de estudio: Diagnostic_studies / Etiology_studies / Screening_studies Aspecto: Patient_preference Límite: Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Minerva Med Año: 2021 Tipo del documento: Article País de afiliación: Italia