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Gut Resistome of Preschool Children After Prolonged Mass Azithromycin Distribution: A Cluster-randomized Trial.
Arzika, Ahmed M; Maliki, Ramatou; Abdou, Amza; Mankara, Alio K; Harouna, Abdoul N; Cook, Catherine; Hinterwirth, Armin; Worden, Lee; Zhong, Lina; Chen, Cindi; Ruder, Kevin; Zhou, Zhaoxia; Lebas, Elodie; O'Brien, Kieran S; Oldenburg, Catherine E; Le, Victoria; Arnold, Benjamin F; Porco, Travis C; Keenan, Jeremy D; Lietman, Thomas M; Doan, Thuy.
Afiliación
  • Arzika AM; The Carter Center, Niamey, Niger.
  • Maliki R; The Carter Center, Niamey, Niger.
  • Abdou A; Ministry of Health, Niamey, Niger.
  • Mankara AK; Programme National de Santé Oculaire, Niamey, Niger.
  • Harouna AN; The Carter Center, Niamey, Niger.
  • Cook C; The Carter Center, Niamey, Niger.
  • Hinterwirth A; Francis I Proctor Foundation, Universit of California San Francisco, San Francisco, California, USA.
  • Worden L; Francis I Proctor Foundation, Universit of California San Francisco, San Francisco, California, USA.
  • Zhong L; Francis I Proctor Foundation, Universit of California San Francisco, San Francisco, California, USA.
  • Chen C; Francis I Proctor Foundation, Universit of California San Francisco, San Francisco, California, USA.
  • Ruder K; Francis I Proctor Foundation, Universit of California San Francisco, San Francisco, California, USA.
  • Zhou Z; Francis I Proctor Foundation, Universit of California San Francisco, San Francisco, California, USA.
  • Lebas E; Francis I Proctor Foundation, Universit of California San Francisco, San Francisco, California, USA.
  • O'Brien KS; Francis I Proctor Foundation, Universit of California San Francisco, San Francisco, California, USA.
  • Oldenburg CE; Francis I Proctor Foundation, Universit of California San Francisco, San Francisco, California, USA.
  • Le V; Francis I Proctor Foundation, Universit of California San Francisco, San Francisco, California, USA.
  • Arnold BF; Department of Ophthalmology, University of California San Francisco, San Francisco, California, USA.
  • Porco TC; Department of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, California, USA.
  • Keenan JD; Francis I Proctor Foundation, Universit of California San Francisco, San Francisco, California, USA.
  • Lietman TM; Francis I Proctor Foundation, Universit of California San Francisco, San Francisco, California, USA.
  • Doan T; Francis I Proctor Foundation, Universit of California San Francisco, San Francisco, California, USA.
Clin Infect Dis ; 73(7): 1292-1295, 2021 10 05.
Article en En | MEDLINE | ID: mdl-34037753
ABSTRACT
We evaluated the gut resistome of children from communities treated with 10 twice-yearly azithromycin distributions. Although the macrolide resistance remained higher in the azithromycin arm, the selection of non-macrolide resistance observed at earlier time points did not persist. Longitudinal resistance monitoring should be a critical component of mass distribution programs. CLINICAL TRIALS REGISTRATION NCT02047981.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Azitromicina / Antibacterianos Tipo de estudio: Clinical_trials Límite: Child, preschool / Humans Idioma: En Revista: Clin Infect Dis Asunto de la revista: DOENCAS TRANSMISSIVEIS Año: 2021 Tipo del documento: Article País de afiliación: Níger
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Azitromicina / Antibacterianos Tipo de estudio: Clinical_trials Límite: Child, preschool / Humans Idioma: En Revista: Clin Infect Dis Asunto de la revista: DOENCAS TRANSMISSIVEIS Año: 2021 Tipo del documento: Article País de afiliación: Níger