Alzheimer's disease-associated ß-amyloid does not protect against herpes simplex virus 1 infection in the mouse brain.

Bocharova, Olga; Pandit, Narayan P; Molesworth, Kara; Fisher, Aidan; Mychko, Olga; Makarava, Natallia; Baskakov, Ilia V

Bocharova, Olga; Pandit, Narayan P; Molesworth, Kara; Fisher, Aidan; Mychko, Olga; Makarava, Natallia; Baskakov, Ilia V.

Afiliación

Bocharova O; Center for Biomedical Engineering and Technology, University of Maryland School of Medicine, Baltimore, Maryland, USA; Department of Anatomy and Neurobiology, University of Maryland School of Medicine, Baltimore, Maryland, USA.
Pandit NP; Center for Biomedical Engineering and Technology, University of Maryland School of Medicine, Baltimore, Maryland, USA; Department of Anatomy and Neurobiology, University of Maryland School of Medicine, Baltimore, Maryland, USA.
Molesworth K; Center for Biomedical Engineering and Technology, University of Maryland School of Medicine, Baltimore, Maryland, USA; Department of Anatomy and Neurobiology, University of Maryland School of Medicine, Baltimore, Maryland, USA.
Fisher A; Center for Biomedical Engineering and Technology, University of Maryland School of Medicine, Baltimore, Maryland, USA; Department of Anatomy and Neurobiology, University of Maryland School of Medicine, Baltimore, Maryland, USA.
Mychko O; Center for Biomedical Engineering and Technology, University of Maryland School of Medicine, Baltimore, Maryland, USA; Department of Anatomy and Neurobiology, University of Maryland School of Medicine, Baltimore, Maryland, USA.
Makarava N; Center for Biomedical Engineering and Technology, University of Maryland School of Medicine, Baltimore, Maryland, USA; Department of Anatomy and Neurobiology, University of Maryland School of Medicine, Baltimore, Maryland, USA.
Baskakov IV; Center for Biomedical Engineering and Technology, University of Maryland School of Medicine, Baltimore, Maryland, USA; Department of Anatomy and Neurobiology, University of Maryland School of Medicine, Baltimore, Maryland, USA. Electronic address: Baskakov@som.umaryland.edu.

J Biol Chem ; 297(1): 100845, 2021 07.

Article en En | MEDLINE | ID: mdl-34052228

Asunto(s)

Péptidos beta-Amiloides/genética; Precursor de Proteína beta-Amiloide/genética; Interacciones Huésped-Patógeno/genética; Virosis/genética; Enfermedad de Alzheimer/complicaciones; Enfermedad de Alzheimer/genética; Enfermedad de Alzheimer/patología; Enfermedad de Alzheimer/virología; Animales; Astrocitos/metabolismo; Astrocitos/patología; Encéfalo/patología; Encéfalo/virología; Modelos Animales de Enfermedad; Herpes Simple/genética; Herpes Simple/patología; Herpes Simple/virología; Herpesvirus Humano 1/genética; Herpesvirus Humano 1/patogenicidad; Humanos; Ratones; Ratones Transgénicos; Microglía/patología; Microglía/virología; Presenilina-1/genética; Virosis/complicaciones; Virosis/patología; Virosis/virología; Replicación Viral/genética

Palabras clave

5XFAD mice; Alzheimer's disease; Aß aggregates; amyloid precursor protein; astrocytes; herpes simplex virus 1; microglia

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Virosis / Péptidos beta-Amiloides / Precursor de Proteína beta-Amiloide / Interacciones Huésped-Patógeno Tipo de estudio: Risk_factors_studies Límite: Animals / Humans Idioma: En Revista: J Biol Chem Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos

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