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Double mutations in the H9N2 avian influenza virus PB2 gene act cooperatively to increase viral host adaptation and replication for human infections.
Elgendy, Emad Mohamed; Arai, Yasuha; Kawashita, Norihito; Isobe, Ayana; Daidoji, Tomo; Ibrahim, Madiha Salah; Ono, Takao; Takagi, Tatsuya; Nakaya, Takaaki; Matsumoto, Kazuhiko; Watanabe, Yohei.
Afiliación
  • Elgendy EM; Department of Infectious Diseases, Graduate School of Medical Sciences, Kyoto Prefectural University of Medicine, Kyoto, Japan.
  • Arai Y; Department of Microbiology and Immunology, Faculty of Veterinary Medicine, Damanhour University, Damanhour, Egypt.
  • Kawashita N; Department of Infectious Diseases, Graduate School of Medical Sciences, Kyoto Prefectural University of Medicine, Kyoto, Japan.
  • Isobe A; Graduate School of Pharmaceutical Sciences, Osaka University, Osaka, Japan.
  • Daidoji T; Faculty of Science and Engineering, Kindai University, Osaka, Japan.
  • Ibrahim MS; Department of Infectious Diseases, Graduate School of Medical Sciences, Kyoto Prefectural University of Medicine, Kyoto, Japan.
  • Ono T; Department of Infectious Diseases, Graduate School of Medical Sciences, Kyoto Prefectural University of Medicine, Kyoto, Japan.
  • Takagi T; Department of Microbiology and Immunology, Faculty of Veterinary Medicine, Damanhour University, Damanhour, Egypt.
  • Nakaya T; The Institute of Scientific and Industrial Research, Osaka University, Osaka, Japan.
  • Matsumoto K; Graduate School of Pharmaceutical Sciences, Osaka University, Osaka, Japan.
  • Watanabe Y; Department of Infectious Diseases, Graduate School of Medical Sciences, Kyoto Prefectural University of Medicine, Kyoto, Japan.
J Gen Virol ; 102(6)2021 06.
Article en En | MEDLINE | ID: mdl-34061017
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Proteínas Virales / Replicación Viral / ARN Polimerasa Dependiente del ARN / Gripe Humana / Subtipo H9N2 del Virus de la Influenza A / Adaptación al Huésped Tipo de estudio: Risk_factors_studies Límite: Animals / Humans Idioma: En Revista: J Gen Virol Año: 2021 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Proteínas Virales / Replicación Viral / ARN Polimerasa Dependiente del ARN / Gripe Humana / Subtipo H9N2 del Virus de la Influenza A / Adaptación al Huésped Tipo de estudio: Risk_factors_studies Límite: Animals / Humans Idioma: En Revista: J Gen Virol Año: 2021 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Reino Unido