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Enhanced Efficacy of Aurora Kinase Inhibitors in G2/M Checkpoint Deficient TP53 Mutant Uterine Carcinomas Is Linked to the Summation of LKB1-AKT-p53 Interactions.
Lynch, Katherine N; Liu, Joyce F; Kesten, Nikolas; Chow, Kin-Hoe; Shetty, Aniket; He, Ruiyang; Afreen, Mosammat Faria; Yuan, Liping; Matulonis, Ursula A; Growdon, Whitfield B; Muto, Michael G; Horowitz, Neil S; Feltmate, Colleen M; Worley, Michael J; Berkowitz, Ross S; Crum, Christopher P; Rueda, Bo R; Hill, Sarah J.
Afiliación
  • Lynch KN; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA.
  • Liu JF; Division of Molecular and Cellular Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA.
  • Kesten N; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA.
  • Chow KH; Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA.
  • Shetty A; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA.
  • He R; Center for Functional Cancer Epigenetics, Dana-Farber Cancer Institute, Boston, MA 02215, USA.
  • Afreen MF; Center for Patient Derived Models, Dana-Farber Cancer Institute, Boston, MA 02215, USA.
  • Yuan L; Center for Patient Derived Models, Dana-Farber Cancer Institute, Boston, MA 02215, USA.
  • Matulonis UA; Department of Biochemistry, Cambridge University, Cambridge CB2 1QW, UK.
  • Growdon WB; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA.
  • Muto MG; Division of Molecular and Cellular Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA.
  • Horowitz NS; Department of Pathology, Brigham and Women's Hospital, Boston, MA 02115, USA.
  • Feltmate CM; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA.
  • Worley MJ; Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA.
  • Berkowitz RS; Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Massachusetts General Hospital, Boston, MA 02114, USA.
  • Crum CP; Vincent Center for Reproductive Biology, Department of Obstetrics and Gynecology, Massachusetts General Hospital, Boston, MA 02114, USA.
  • Rueda BR; Obstetrics, Gynecology and Reproductive Biology, Harvard Medical School, Boston, MA 02115, USA.
  • Hill SJ; Obstetrics, Gynecology and Reproductive Biology, Harvard Medical School, Boston, MA 02115, USA.
Cancers (Basel) ; 13(9)2021 May 03.
Article en En | MEDLINE | ID: mdl-34063609

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Cancers (Basel) Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Suiza

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Cancers (Basel) Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Suiza