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Rational Alteration of Pharmacokinetics of Chiral Fluorinated and Deuterated Derivatives of Emixustat for Retinal Therapy.
Blum, Eliav; Zhang, Jianye; Zaluski, Jordan; Einstein, David E; Korshin, Edward E; Kubas, Adam; Gruzman, Arie; Tochtrop, Gregory P; Kiser, Philip D; Palczewski, Krzysztof.
Afiliación
  • Blum E; Department of Chemistry, Faculty of Exact Sciences, Bar-Ilan University, Ramat-Gan 5290002, Israel.
  • Zhang J; Department of Ophthalmology, Gavin Herbert Eye Institute, University of California, Irvine, California 92697, United States.
  • Zaluski J; Department of Chemistry, Case Western Reserve University, Cleveland, Ohio 44106, United States.
  • Einstein DE; Department of Physiology and Biophysics, University of California, Irvine, California 92697, United States.
  • Korshin EE; Research Service, VA Long Beach Healthcare System, Long Beach, California 90822, United States.
  • Kubas A; Department of Chemistry, Faculty of Exact Sciences, Bar-Ilan University, Ramat-Gan 5290002, Israel.
  • Gruzman A; Institute of Physical Chemistry, Polish Academy of Sciences, Kasprzaka 44/52, Warsaw 01-224, Poland.
  • Tochtrop GP; Department of Chemistry, Faculty of Exact Sciences, Bar-Ilan University, Ramat-Gan 5290002, Israel.
  • Kiser PD; Department of Chemistry, Case Western Reserve University, Cleveland, Ohio 44106, United States.
  • Palczewski K; Department of Ophthalmology, Gavin Herbert Eye Institute, University of California, Irvine, California 92697, United States.
J Med Chem ; 64(12): 8287-8302, 2021 06 24.
Article en En | MEDLINE | ID: mdl-34081480
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Éteres Fenílicos / Propanolaminas / Ojo Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: J Med Chem Asunto de la revista: QUIMICA Año: 2021 Tipo del documento: Article País de afiliación: Israel
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Éteres Fenílicos / Propanolaminas / Ojo Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: J Med Chem Asunto de la revista: QUIMICA Año: 2021 Tipo del documento: Article País de afiliación: Israel