Clinical findings in dogs diagnosed with leptospirosis in England.
Vet Rec
; 189(7): e452, 2021 Oct.
Article
en En
| MEDLINE
| ID: mdl-34085284
ABSTRACT
BACKGROUND:
Leptospirosis is a zoonotic disease of worldwide importance. This study describes the clinical findings and outcome of dogs diagnosed with leptospirosis in England.METHODS:
Retrospective review of medical records of dogs diagnosed with leptospirosis from a single referral hospital located in Eastern England.RESULTS:
Thirty-eight dogs met the inclusion criteria. Clinical signs included inappetence (76%), vomiting (68%), lethargy (58%), polydipsia and polyuria (18%) and abdominal pain (16%). Disease manifestations included hepatic and renal involvement (47%), hepatic only (37%), renal only (16%); no dogs were found to have respiratory involvement. Clinicopathological findings at presentation included anaemia (42%), thrombocytopenia (43%), increased alanine transaminase activity (ALT) (66%), hyperbilirubinemia (55%), azotaemia (68%), hypoalbuminaemia (49%) and glucosuria (32%). Seven serovars of Leptospira interrogans or Leptospira kirschneri were detected; the most prevalent was Copenhageni (48%). Seventy-one percent survived to discharge. Dogs in the non-surviving group had a higher creatinine at presentation compared to survivors (p = 0.02).CONCLUSIONS:
Copenhageni was the most prevalent serovar in this population. This supports the use of a vaccine including this serovar, in this region. Renal involvement was associated with reduced survival to discharge. A hepatic only form was common in this population, and leptospirosis should be included as a differential diagnosis for dogs suffering with a hepatopathy. No cases had significant pulmonary involvement, but ongoing clinical vigilance for this disease manifestation is essential.Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Enfermedades de los Perros
/
Leptospira
/
Leptospira interrogans
/
Leptospirosis
Tipo de estudio:
Diagnostic_studies
/
Observational_studies
/
Risk_factors_studies
Límite:
Animals
Idioma:
En
Revista:
Vet Rec
Año:
2021
Tipo del documento:
Article
País de afiliación:
Reino Unido