HIV-1 sequences in lentiviral vector genomes can be substantially reduced without compromising transduction efficiency.

Sertkaya, Helin; Ficarelli, Mattia; Sweeney, Nathan P; Parker, Hannah; Vink, Conrad A; Swanson, Chad M

Sertkaya, Helin; Ficarelli, Mattia; Sweeney, Nathan P; Parker, Hannah; Vink, Conrad A; Swanson, Chad M.

Afiliación

Sertkaya H; Department of Infectious Diseases, King's College London, London, SE1 9RT, UK.
Ficarelli M; Department of Infectious Diseases, King's College London, London, SE1 9RT, UK.
Sweeney NP; Cell & Gene Therapy Platform, Medicinal Science and Technology, GSK, Stevenage, SG1 2NY, UK.
Parker H; Department of Infectious Diseases, King's College London, London, SE1 9RT, UK.
Vink CA; Cell & Gene Therapy Platform, Medicinal Science and Technology, GSK, Stevenage, SG1 2NY, UK. conrad.x.vink@gsk.com.
Swanson CM; Department of Infectious Diseases, King's College London, London, SE1 9RT, UK. chad.swanson@kcl.ac.uk.

Sci Rep ; 11(1): 12067, 2021 06 08.

Article en En | MEDLINE | ID: mdl-34103612

Asunto(s)

Vectores Genéticos/genética; Genoma Viral; VIH-1/genética; Transducción Genética; Células HEK293; Humanos

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Transducción Genética / VIH-1 / Genoma Viral / Vectores Genéticos Límite: Humans Idioma: En Revista: Sci Rep Año: 2021 Tipo del documento: Article País de afiliación: Reino Unido

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