Adverse pregnancy and maternal outcomes in women with hidradenitis suppurativa.
J Am Acad Dermatol
; 86(1): 46-54, 2022 01.
Article
en En
| MEDLINE
| ID: mdl-34126093
ABSTRACT
BACKGROUND:
Hidradenitis suppurativa (HS) disproportionately affects women of childbearing age. However, pregnancy and maternal outcomes for women with HS are unknown.OBJECTIVE:
To compare risk of adverse pregnancy and maternal outcomes among women with and without HS and to evaluate the influence of comorbid conditions.METHODS:
Retrospective cohort analysis between January 1, 2011, and September 30, 2015.RESULTS:
Compared to control pregnancies (n = 64,218), HS pregnancies (n = 1862) had a higher risk of spontaneous abortion (15.5% vs 11.3%), preterm birth (9.1% vs 6.7%), gestational diabetes mellitus (11.6% vs 8.4%), gestational hypertension (6.1% vs 4.4%), preeclampsia (6.6% vs 3.8%), and cesarean section (32.4% vs 27.1%). Relative risk of some pregnancy and maternal outcomes were attenuated after comorbidity adjustment. In the fully adjusted model, HS pregnancies were independently associated with spontaneous abortion (odds ratio, 1.20; 95% CI, 1.04-1.38), gestational diabetes mellitus (odds ratio, 1.26; 95% CI, 1.07-1.48), and cesarean section (odds ratio, 1.09; 95% CI, 1.004-1.17).LIMITATIONS:
We could not evaluate potential influences of disease duration, activity, or severity. Newborn outcomes could not be evaluated.CONCLUSION:
HS appears to be an independent risk factor for adverse pregnancy and maternal outcomes. This risk is influenced by comorbidities that may be modifiable with early identification and management.Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Aborto Espontáneo
/
Diabetes Gestacional
/
Hidradenitis Supurativa
/
Nacimiento Prematuro
Tipo de estudio:
Etiology_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Límite:
Female
/
Humans
/
Newborn
/
Pregnancy
Idioma:
En
Revista:
J Am Acad Dermatol
Año:
2022
Tipo del documento:
Article