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Cyclotron-produced 68Ga from enriched 68Zn foils.
Siikanen, Jonathan; Jussing, Emma; Milton, Stefan; Steiger, Carsten; Ulin, Johan; Jonsson, Cathrine; Samén, Erik; Tran, Thuy A.
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  • Siikanen J; Karolinska University Hospital, Department of Medical Radiation Physics and Nuclear Medicine, Eugeniavägen 3, SE- 171 76, Stockholm, Sweden; Karolinska Institutet, Department of Oncology and Pathology, Akademiska stråket 1, SE-171 64, Stockholm, Sweden. Electronic address: jonathan.siikanen@ki.se.
  • Jussing E; Karolinska University Hospital, Department of Radiopharmacy, Stockholm, Sweden, Akademiska stråket 1, SE-171 64, Stockholm, Sweden; Karolinska Institutet, Department of Oncology and Pathology, Akademiska stråket 1, SE-171 64, Stockholm, Sweden.
  • Milton S; Karolinska University Hospital, Department of Radiopharmacy, Stockholm, Sweden, Akademiska stråket 1, SE-171 64, Stockholm, Sweden; Karolinska Institutet, Department of Oncology and Pathology, Akademiska stråket 1, SE-171 64, Stockholm, Sweden.
  • Steiger C; Karolinska University Hospital, Department of Radiopharmacy, Stockholm, Sweden, Akademiska stråket 1, SE-171 64, Stockholm, Sweden; Karolinska Institutet, Department of Clinical Neuroscience, Akademiska stråket 1, SE-171 64, Stockholm, Sweden.
  • Ulin J; Karolinska Institutet, Department of Clinical Neuroscience, Akademiska stråket 1, SE-171 64, Stockholm, Sweden.
  • Jonsson C; Karolinska University Hospital, Department of Medical Radiation Physics and Nuclear Medicine, Eugeniavägen 3, SE- 171 76, Stockholm, Sweden.
  • Samén E; Karolinska University Hospital, Department of Radiopharmacy, Stockholm, Sweden, Akademiska stråket 1, SE-171 64, Stockholm, Sweden; Karolinska Institutet, Department of Oncology and Pathology, Akademiska stråket 1, SE-171 64, Stockholm, Sweden.
  • Tran TA; Karolinska University Hospital, Department of Radiopharmacy, Stockholm, Sweden, Akademiska stråket 1, SE-171 64, Stockholm, Sweden; Karolinska Institutet, Department of Oncology and Pathology, Akademiska stråket 1, SE-171 64, Stockholm, Sweden.
Appl Radiat Isot ; 176: 109825, 2021 Oct.
Article en En | MEDLINE | ID: mdl-34157495
The growing need and limited availability of generator produced 68Ga (T1/2 = 68 min) for PET has provided the impetus for alternative, high output, 68Ga production routes such as charge particle activation of enriched 68Zn using PET cyclotrons. The work presents a rapid production method for clinically useful 68Ga for radiolabeling. The focus is also to expand the production capacity of cyclotron solid target-produced 68Ga over generator produced and liquid solutions targets by using enriched 68Zn-foils that minimizes target preparation.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Isótopos de Zinc / Ciclotrones / Radioisótopos de Galio Idioma: En Revista: Appl Radiat Isot Asunto de la revista: MEDICINA NUCLEAR / SAUDE AMBIENTAL Año: 2021 Tipo del documento: Article Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Isótopos de Zinc / Ciclotrones / Radioisótopos de Galio Idioma: En Revista: Appl Radiat Isot Asunto de la revista: MEDICINA NUCLEAR / SAUDE AMBIENTAL Año: 2021 Tipo del documento: Article Pais de publicación: Reino Unido