One Health Approach of Melioidosis and Gastrointestinal Parasitic Infections from Macaca fascicularis to Human at Kosumpee Forest Park, Maha Sarakham, Thailand.

ABSTRACT

BACKGROUND AND OBJECTIVES: Gastrointestinal parasitic and melioidosis infections are major causes of morbidity and mortality from infectious disease in rural areas, especially in northeastern Thailand. Both diseases are zoonotic giving rise to health problems in both long-tailed macaques and in humans. In Thailand, macaques have adapted to live and share space with humans and can spread some zoonoses to humans. Therefore, this research aimed to measure the prevalence of gastrointestinal parasitic infections and melioidosis in long-tailed macaques at Kosumpee Forest Park and measure associated risk factors of their diseases among people in this area. METHODS: This study was conducted at Kosumpee Forest Park, Maha Sarakham, Thailand. Twenty-eight blood samples and 135 fecal samples were collected from free-ranging long-tailed macaques. Blood samples were tested by indirect hemagglutination test and fecal samples were analyzed by formalin-ethyl acetate concentration technique. A cross-sectional study was conducted among 350 respondents who were involved with the Forest Park using a multi-stage stratified random sampling method and performed to measure knowledge, attitude, and practice toward the zoonoses among the respondents. RESULTS: It was found that seroprevalence of melioidosis was 57.1% from macaque samples. The prevalence of gastrointestinal parasites infection was 35.11% from fecces samples, including Strongyloides spp. (15.27%), Trichuris spp. (22.9%), hookworm (4.58%) and Ascarid spp. (1.53%). KAP study indicated that the level of knowledge related to melioidosis and gastrointestinal parasites of people in the area was very low and moderate, respectively. The attitude of respondents who were aware of the diseases was at a moderate level for melioidosis and a high level for parasitic infection. CONCLUSION: The study therefore emphasizes the importance of one health approach for diagnosis, surveillance and management of zoonotic diseases to promote the development of hygiene measures and to educate people in the community around Kosumpee Forest Park.