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Rapid generation of potent antibodies by autonomous hypermutation in yeast.
Wellner, Alon; McMahon, Conor; Gilman, Morgan S A; Clements, Jonathan R; Clark, Sarah; Nguyen, Kianna M; Ho, Ming H; Hu, Vincent J; Shin, Jung-Eun; Feldman, Jared; Hauser, Blake M; Caradonna, Timothy M; Wingler, Laura M; Schmidt, Aaron G; Marks, Debora S; Abraham, Jonathan; Kruse, Andrew C; Liu, Chang C.
Afiliación
  • Wellner A; Department of Biomedical Engineering, University of California, Irvine, CA, USA.
  • McMahon C; Department of Biological Chemistry and Molecular Pharmacology, Blavatnik Institute, Harvard Medical School, Boston, MA, USA.
  • Gilman MSA; Vertex Pharmaceuticals, Boston, MA, USA.
  • Clements JR; Department of Biological Chemistry and Molecular Pharmacology, Blavatnik Institute, Harvard Medical School, Boston, MA, USA.
  • Clark S; Department of Biomedical Engineering, University of California, Irvine, CA, USA.
  • Nguyen KM; Department of Microbiology, Blavatnik Institute, Harvard Medical School, Boston, MA, USA.
  • Ho MH; Department of Biomedical Engineering, University of California, Irvine, CA, USA.
  • Hu VJ; Department of Biomedical Engineering, University of California, Irvine, CA, USA.
  • Shin JE; Department of Biomedical Engineering, University of California, Irvine, CA, USA.
  • Feldman J; Department of Systems Biology, Harvard Medical School, Boston, MA, USA.
  • Hauser BM; Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, USA.
  • Caradonna TM; Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, USA.
  • Wingler LM; Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, USA.
  • Schmidt AG; Department of Medicine, Duke University Medical Center, Durham, NC, USA.
  • Marks DS; Howard Hughes Medical Institute, Duke University Medical Center, Durham, NC, USA.
  • Abraham J; Department of Pharmacology and Cancer Biology, Duke University, Durham, NC, USA.
  • Kruse AC; Department of Microbiology, Blavatnik Institute, Harvard Medical School, Boston, MA, USA.
  • Liu CC; Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, USA.
Nat Chem Biol ; 17(10): 1057-1064, 2021 10.
Article en En | MEDLINE | ID: mdl-34168368
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Proteínas Recombinantes / Ingeniería de Proteínas / Formación de Anticuerpos Límite: Humans Idioma: En Revista: Nat Chem Biol Asunto de la revista: BIOLOGIA / QUIMICA Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Proteínas Recombinantes / Ingeniería de Proteínas / Formación de Anticuerpos Límite: Humans Idioma: En Revista: Nat Chem Biol Asunto de la revista: BIOLOGIA / QUIMICA Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos