A Patient With Regressed Diffuse Large B-Cell Lymphoma and Aggressive Follicular Lymphoma.

Diffuse large B-cell lymphoma (DLBCL) and follicular lymphoma (FL) are the two most aggressive forms of non-Hodgkin lymphomas (NHLs). Spontaneous remission of DLBCL is a rare phenomenon. Immune system activation has been observed to play a significant role in the regression of untreated disease on some occasions. We present a case of DLBCL in a 75-year-old male patient who has been free of disease for two months without any treatment due to possible immune-related mechanism, but later he presented with FL.