Obstructive Sleep Apnea and Cardiovascular Disease.
Clin Geriatr Med
; 37(3): 445-456, 2021 08.
Article
en En
| MEDLINE
| ID: mdl-34210449
ABSTRACT
Obstructive sleep apnea (OSA) presents as repetitive interruptions of ventilation >10 seconds during sleep as a result of upper airway obstruction resulting in increased respiratory effort. Intermittent hypoxia causes physiologic changes resulting in increased catecholamine production, increased total peripheral resistance, tachycardia, and increased venous return, leading to increased cardiac output, hypertension, tachyarrhythmias, left ventricular hypertrophy, and heart failure. OSA causes an abnormal dip on 24-hour ambulatory blood pressure monitoring. Definitive diagnosis is made by polysomnography. Continuous positive airway pressure (CPAP) remains the first-line treatment. Effective treatment using CPAP reduces blood pressure and is indispensable for proper management of atrial fibrillation.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Enfermedades Cardiovasculares
/
Apnea Obstructiva del Sueño
/
Presión de las Vías Aéreas Positiva Contínua
/
Hipertensión
Tipo de estudio:
Etiology_studies
Límite:
Aged
/
Humans
Idioma:
En
Revista:
Clin Geriatr Med
Asunto de la revista:
GERIATRIA
Año:
2021
Tipo del documento:
Article