Pharmacoepidemiological methods for computing the duration of pharmacological prescriptions using secondary data sources.
Eur J Clin Pharmacol
; 77(12): 1805-1814, 2021 Dec.
Article
en En
| MEDLINE
| ID: mdl-34247270
ABSTRACT
PURPOSE:
In pharmacoepidemiology, correctly defining the exposure period of pharmacological treatment is a challenging step when information on the time in treatment is missing or incomplete.METHODS:
In this review, we describe several methods for defining exposure to pharmacological treatments using secondary data sources that lack such information. RESULTS ANDCONCLUSION:
Several methods for assessing the duration of redeemed prescriptions and combining them into temporal sequences are available. We present a set of considerations to make researchers aware of the potentials and pitfalls of these methods that may aid in minimizing biases in research using these methods. Additionally, we highlight that, to date, there is no one-size-fits-all solution. Thus, the choice of method should be based on their area of applicability combined with a careful mapping to the research scenario under investigation.Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Prescripciones de Medicamentos
/
Recolección de Datos
/
Farmacoepidemiología
/
Medicamentos bajo Prescripción
Límite:
Humans
Idioma:
En
Revista:
Eur J Clin Pharmacol
Año:
2021
Tipo del documento:
Article
País de afiliación:
Dinamarca
Pais de publicación:
ALEMANHA
/
ALEMANIA
/
DE
/
DEUSTCHLAND
/
GERMANY