Tandem aza-Heck Suzuki and carbonylation reactions of <i>O</i>-phenyl hydroxamic ethers: complex lactams <i>via</i> carboamination.

Gao, Run-Duo; Shuler, Scott A; Watson, Donald A

Tandem aza-Heck Suzuki and carbonylation reactions of O-phenyl hydroxamic ethers: complex lactams via carboamination.

Gao, Run-Duo; Shuler, Scott A; Watson, Donald A.

Afiliación

Gao RD; Department of Chemistry and Biochemistry, University of Delaware Newark DE 19716 USA dawatson@udel.edu.
Shuler SA; Department of Chemistry and Biochemistry, University of Delaware Newark DE 19716 USA dawatson@udel.edu.
Watson DA; Department of Chemistry and Biochemistry, University of Delaware Newark DE 19716 USA dawatson@udel.edu.

Chem Sci ; 12(25): 8859-8864, 2021 Jul 01.

Article en En | MEDLINE | ID: mdl-34257886

ABSTRACT

ABSTRACT

The palladium-catalysed tandem aza-Heck-Suzuki and aza-Heck-carbonylation reactions of O-phenyl hydroxamic ethers are reported. These formal alkene carboamination reactions provide highly versatile access to wide range complex, stereogenic secondary lactams and exhibit outstanding functional group tolerance and high diastereoselectivity.

Texto completo

Añadir a Mi BVS

Imprimir

XML

PubMed Links

Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Chem Sci Año: 2021 Tipo del documento: Article Pais de publicación: ENGLAND / ESCOCIA / GB / GREAT BRITAIN / INGLATERRA / REINO UNIDO / SCOTLAND / UK / UNITED KINGDOM

Texto completo

Añadir a Mi BVS

Imprimir

XML

PubMed Links

Buscar en Google