MicroRNA miR-29c regulates RAG1 expression and modulates V(D)J recombination during B cell development.

Kumari, Rupa; Roy, Urbi; Desai, Sagar; Nilavar, Namrata M; Van Nieuwenhuijze, Annemarie; Paranjape, Amita; Radha, Gudapureddy; Bawa, Pushpinder; Srivastava, Mrinal; Nambiar, Mridula; Balaji, Kithiganahalli Narayanaswamy; Liston, Adrian; Choudhary, Bibha; Raghavan, Sathees C

Kumari, Rupa; Roy, Urbi; Desai, Sagar; Nilavar, Namrata M; Van Nieuwenhuijze, Annemarie; Paranjape, Amita; Radha, Gudapureddy; Bawa, Pushpinder; Srivastava, Mrinal; Nambiar, Mridula; Balaji, Kithiganahalli Narayanaswamy; Liston, Adrian; Choudhary, Bibha; Raghavan, Sathees C.

Afiliación

Kumari R; Department of Biochemistry, Indian Institute of Science, Bangalore 560012, India.
Roy U; Department of Biochemistry, Indian Institute of Science, Bangalore 560012, India.
Desai S; Institute of Bioinformatics and Applied Biotechnology, Bangalore 560100, India; Manipal Academy of Higher Education, Manipal, Karnataka 576104, India.
Nilavar NM; Department of Biochemistry, Indian Institute of Science, Bangalore 560012, India.
Van Nieuwenhuijze A; Department of Microbiology and Immunology, Laboratory of Adaptive Immunity, KU Leuven, Leuven, Belgium.
Paranjape A; Department of Biochemistry, Indian Institute of Science, Bangalore 560012, India.
Radha G; Department of Biochemistry, Indian Institute of Science, Bangalore 560012, India.
Bawa P; Institute of Bioinformatics and Applied Biotechnology, Bangalore 560100, India.
Srivastava M; TIFR Centre for Interdisciplinary Sciences, Tata Institute of Fundamental Research (TIFR), Hyderabad 500046, India.
Nambiar M; Department of Biology, Indian Institute of Science Education and Research, Pune, India.
Balaji KN; Department of Microbiology and Cell Biology, Indian Institute of Science, Bangalore 560012, India.
Liston A; Immunology Programme, Babraham Institute, Cambridge, United Kingdom.
Choudhary B; Institute of Bioinformatics and Applied Biotechnology, Bangalore 560100, India. Electronic address: vibha@ibab.ac.in.
Raghavan SC; Department of Biochemistry, Indian Institute of Science, Bangalore 560012, India. Electronic address: sathees@iisc.ac.in.

Cell Rep ; 36(2): 109390, 2021 07 13.

Article en En | MEDLINE | ID: mdl-34260911

Asunto(s)

Linfocitos B/metabolismo; Regulación de la Expresión Génica; Proteínas de Homeodominio/genética; MicroARNs/metabolismo; Recombinación V(D)J/genética; Regiones no Traducidas 3'/genética; Animales; Linfocitos B/citología; Secuencia de Bases; Sistemas CRISPR-Cas/genética; Línea Celular Tumoral; Proteínas de Homeodominio/metabolismo; Humanos; Luciferasas/metabolismo; Linfocitos/metabolismo; Ratones Endogámicos BALB C; Ratones Endogámicos C57BL; MicroARNs/genética; Procesamiento Postranscripcional del ARN/genética

Palabras clave

B cell development; RAG complex; epigenetic regulation; immunoglobulin diversity; lymphoid system; miRNA

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Linfocitos B / Regulación de la Expresión Génica / Proteínas de Homeodominio / MicroARNs / Recombinación V(D)J Límite: Animals / Humans Idioma: En Revista: Cell Rep Año: 2021 Tipo del documento: Article País de afiliación: India Pais de publicación: Estados Unidos

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