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The ubiquitous mitochondrial protein unfoldase CLPX regulates erythroid heme synthesis by control of iron utilization and heme synthesis enzyme activation and turnover.
Rondelli, Catherine M; Perfetto, Mark; Danoff, Aidan; Bergonia, Hector; Gillis, Samantha; O'Neill, Leah; Jackson, Laurie; Nicolas, Gael; Puy, Herve; West, Richard; Phillips, John D; Yien, Yvette Y.
Afiliación
  • Rondelli CM; Department of Biological Sciences, University of Delaware, Newark, Delaware, USA.
  • Perfetto M; Department of Biological Sciences, University of Delaware, Newark, Delaware, USA; Pittsburgh Heart, Lung and Blood Vascular Medicine Institute and Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
  • Danoff A; Department of Biological Sciences, University of Delaware, Newark, Delaware, USA.
  • Bergonia H; Division of Hematology, University of Utah School of Medicine, Salt Lake City, Utah, USA.
  • Gillis S; Department of Biological Sciences, University of Delaware, Newark, Delaware, USA.
  • O'Neill L; Department of Biological Sciences, University of Delaware, Newark, Delaware, USA.
  • Jackson L; Division of Hematology, University of Utah School of Medicine, Salt Lake City, Utah, USA.
  • Nicolas G; Centre de Recherche sur l'inflammation, Université Paris Diderot, Site Bichat, Sorbonne Paris Cité, Paris, France.
  • Puy H; Centre de Recherche sur l'inflammation, Université Paris Diderot, Site Bichat, Sorbonne Paris Cité, Paris, France; Centre Français des Porphyries, Hôpital Louis Mourier, APHP, Colombes, France.
  • West R; Delaware Biotechnology Institute, University of Delaware, Newark, Delaware, USA.
  • Phillips JD; Division of Hematology, University of Utah School of Medicine, Salt Lake City, Utah, USA.
  • Yien YY; Department of Biological Sciences, University of Delaware, Newark, Delaware, USA; Pittsburgh Heart, Lung and Blood Vascular Medicine Institute and Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA. Electronic address: yieny@pitt.edu.
J Biol Chem ; 297(2): 100972, 2021 08.
Article en En | MEDLINE | ID: mdl-34280433
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Leucemia Eritroblástica Aguda / Endopeptidasa Clp / Ferroquelatasa / 5-Aminolevulinato Sintetasa / Hemo / Hierro / Mitocondrias Límite: Animals Idioma: En Revista: J Biol Chem Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Leucemia Eritroblástica Aguda / Endopeptidasa Clp / Ferroquelatasa / 5-Aminolevulinato Sintetasa / Hemo / Hierro / Mitocondrias Límite: Animals Idioma: En Revista: J Biol Chem Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos