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Seroprevalence of hepatitis B virus infection, anti-HCV antibodies and HIV and knowledge among people who use drugs attending methadone therapy clinic in Tanzania; a cross-sectional study.
Kilonzo, Semvua B; Gunda, Daniel W; Majinge, David C; Jaka, Hyasinta; Manyiri, Paulina M; Kalokola, Fredrick; Mtui, Grahame; Shao, Elichilia R; Bakshi, Fatma A; Stephano, Alex.
Afiliación
  • Kilonzo SB; Department of Medicine, Catholic University of Health and Allied Sciences, P.O Box 1464, Mwanza, Tanzania. sekipcb@yahoo.com.
  • Gunda DW; Department of Medicine, Bugando Medical Center, P.O Box 1370, Mwanza, Tanzania. sekipcb@yahoo.com.
  • Majinge DC; Department of Medicine, Catholic University of Health and Allied Sciences, P.O Box 1464, Mwanza, Tanzania.
  • Jaka H; Department of Medicine, Bugando Medical Center, P.O Box 1370, Mwanza, Tanzania.
  • Manyiri PM; Department of Medicine, Catholic University of Health and Allied Sciences, P.O Box 1464, Mwanza, Tanzania.
  • Kalokola F; Department of Medicine, Bugando Medical Center, P.O Box 1370, Mwanza, Tanzania.
  • Mtui G; Department of Medicine, Catholic University of Health and Allied Sciences, P.O Box 1464, Mwanza, Tanzania.
  • Shao ER; Department of Medicine, Bugando Medical Center, P.O Box 1370, Mwanza, Tanzania.
  • Bakshi FA; Department of Medicine, Catholic University of Health and Allied Sciences, P.O Box 1464, Mwanza, Tanzania.
  • Stephano A; Department of Medicine, Bugando Medical Center, P.O Box 1370, Mwanza, Tanzania.
BMC Infect Dis ; 21(1): 699, 2021 Jul 21.
Article en En | MEDLINE | ID: mdl-34289801
BACKGROUND: Methadone therapy clinics have been recently introduced in Tanzania, aiming at reducing risk behaviors and infection rates of viral hepatitis and HIV among people who use drugs. The objective of this study was to estimate the prevalence, associated factors and knowledge level of these conditions among people who use drugs attending a methadone clinic in Tanzania. METHODS: We enrolled 253 People who using drugs receiving Methadone therapy. Clinical data was retrospectively collected from the medical records and face-to face interviews were conducted to determine the behavioral risk factors and respondents' knowledge on viral hepatitis and HIV. RESULTS: An overall seroprevalence of viral hepatitis (either hepatitis B surface antigen or anti-hepatitis C virus) was 6.3%, while that of hepatitis B virus mono infection was 3.5% and anti-hepatitis C antibodies was 3.5%. Seroprevalence of HIV was 12.6%. Viral hepatitis was strongly predicted by advanced age (> 35 years) (p = 0.02) and staying at Kirumba area (p = 0.004), and HIV infection was predicted by increased age (> 37 years) (p = 0.04) and female sex (p < 0.001). Regarding the knowledge of viral hepatitis, majority of the respondents were unaware of the transmission methods and availability of hepatitis B virus vaccines and only 17% were classified as well informed (provided ≥4 correct answers out of 7 questions). Good knowledge was highly predicted by higher education level of the individual (p = 0.001). CONCLUSIONS: Despite the efforts to curb viral hepatitis and HIV infections through Methadone clinics, infection rates among people who use drugs are still high and the general knowledge on preventive measures is inadequate.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Infecciones por VIH / Conocimientos, Actitudes y Práctica en Salud / Hepatitis C / Anticuerpos contra la Hepatitis C / Consumidores de Drogas / Hepatitis B / Metadona Tipo de estudio: Observational_studies / Prevalence_studies / Prognostic_studies / Qualitative_research / Risk_factors_studies Límite: Adolescent / Adult / Female / Humans / Male / Middle aged País/Región como asunto: Africa Idioma: En Revista: BMC Infect Dis Asunto de la revista: DOENCAS TRANSMISSIVEIS Año: 2021 Tipo del documento: Article País de afiliación: Tanzania Pais de publicación: Reino Unido

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Infecciones por VIH / Conocimientos, Actitudes y Práctica en Salud / Hepatitis C / Anticuerpos contra la Hepatitis C / Consumidores de Drogas / Hepatitis B / Metadona Tipo de estudio: Observational_studies / Prevalence_studies / Prognostic_studies / Qualitative_research / Risk_factors_studies Límite: Adolescent / Adult / Female / Humans / Male / Middle aged País/Región como asunto: Africa Idioma: En Revista: BMC Infect Dis Asunto de la revista: DOENCAS TRANSMISSIVEIS Año: 2021 Tipo del documento: Article País de afiliación: Tanzania Pais de publicación: Reino Unido