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The novel indomethacin derivative CZ-212-3 exerts antitumor effects on castration-resistant prostate cancer by degrading androgen receptor and its variants.
Wang, Hong; Chang, Zhe; Cai, Guo-di; Yang, Ping; Chen, Jiang-He; Yang, Shan-Shu; Guo, Yin-Feng; Wang, Ming-Yu; Zheng, Xue-Hua; Lei, Jin-Ping; Liu, Pei-Qing; Zhao, De-Peng; Wang, Jun-Jian.
Afiliación
  • Wang H; School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou, 510006, China.
  • Chang Z; School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou, 510006, China.
  • Cai GD; School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou, 510006, China.
  • Yang P; State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou, 510060, China.
  • Chen JH; Department of Pathology, Sun Yat-sen University Cancer Center, Guangzhou, 510060, China.
  • Yang SS; School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou, 510006, China.
  • Guo YF; Key Laboratory of Molecular Target and Clinical Pharmacology, School of Pharmaceutical Sciences and the Fifth Affiliated Hospital, Guangzhou Medical University, Guangzhou, 510006, China.
  • Wang MY; School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou, 510006, China.
  • Zheng XH; School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou, 510006, China.
  • Lei JP; Key Laboratory of Molecular Target and Clinical Pharmacology, School of Pharmaceutical Sciences and the Fifth Affiliated Hospital, Guangzhou Medical University, Guangzhou, 510006, China.
  • Liu PQ; School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou, 510006, China.
  • Zhao DP; School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou, 510006, China.
  • Wang JJ; Guangdong Provincial Key Laboratory of New Drug Design and Evaluation, School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou, 510006, China.
Acta Pharmacol Sin ; 43(4): 1024-1032, 2022 Apr.
Article en En | MEDLINE | ID: mdl-34321613
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias de la Próstata Resistentes a la Castración Límite: Humans / Male Idioma: En Revista: Acta Pharmacol Sin Asunto de la revista: FARMACOLOGIA Año: 2022 Tipo del documento: Article País de afiliación: China Pais de publicación: Estados Unidos
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias de la Próstata Resistentes a la Castración Límite: Humans / Male Idioma: En Revista: Acta Pharmacol Sin Asunto de la revista: FARMACOLOGIA Año: 2022 Tipo del documento: Article País de afiliación: China Pais de publicación: Estados Unidos