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BinomiRare: A robust test for association of a rare genetic variant with a binary outcome for mixed models and any case-control proportion.
Sofer, Tamar; Lee, Jiwon; Kurniansyah, Nuzulul; Jain, Deepti; Laurie, Cecelia A; Gogarten, Stephanie M; Conomos, Matthew P; Heavner, Ben; Hu, Yao; Kooperberg, Charles; Haessler, Jeffrey; Vasan, Ramachandran S; Cupples, L Adrienne; Coombes, Brandon J; Seyerle, Amanda; Gharib, Sina A; Chen, Han; O'Connell, Jeffrey R; Zhang, Man; Gottlieb, Daniel J; Psaty, Bruce M; Longstreth, W T; Rotter, Jerome I; Taylor, Kent D; Rich, Stephen S; Guo, Xiuqing; Boerwinkle, Eric; Morrison, Alanna C; Pankow, James S; Johnson, Andrew D; Pankratz, Nathan; Reiner, Alex P; Redline, Susan; Smith, Nicholas L; Rice, Kenneth M; Schifano, Elizabeth D.
Afiliación
  • Sofer T; Department of Medicine, Harvard Medical School, Boston, MA, USA.
  • Lee J; Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
  • Kurniansyah N; Division of Sleep and Circadian Disorders, Brigham and Women's Hospital, Boston, MA, USA.
  • Jain D; Division of Sleep and Circadian Disorders, Brigham and Women's Hospital, Boston, MA, USA.
  • Laurie CA; Division of Sleep and Circadian Disorders, Brigham and Women's Hospital, Boston, MA, USA.
  • Gogarten SM; Department of Biostatistics, University of Washington, Seattle, WA, USA.
  • Conomos MP; Department of Biostatistics, University of Washington, Seattle, WA, USA.
  • Heavner B; Department of Biostatistics, University of Washington, Seattle, WA, USA.
  • Hu Y; Department of Biostatistics, University of Washington, Seattle, WA, USA.
  • Kooperberg C; Department of Biostatistics, University of Washington, Seattle, WA, USA.
  • Haessler J; Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
  • Vasan RS; Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
  • Cupples LA; Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
  • Coombes BJ; Departments of Medicine and Epidemiology, Boston University Schools of Medicine and Public Health, Boston, MA, USA.
  • Seyerle A; Framingham Heart Study, Framingham, MA, USA.
  • Gharib SA; Framingham Heart Study, Framingham, MA, USA.
  • Chen H; Department of Biostatistics, Boston University, Boston, MA, USA.
  • O'Connell JR; Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA.
  • Zhang M; Division of Pharmaceutical Outcomes and Policy, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
  • Gottlieb DJ; Computational Medicine Core, Center for Lung Biology, Department of Medicine, University of Washington, Seattle, WA, USA.
  • Psaty BM; Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX, USA.
  • Longstreth WT; Center for Precision Health, School of Biomedical Informatics, The University of Texas Health Science Center at Houston, Houston, TX, USA.
  • Rotter JI; Department of Medicine, Division of Endocrinology, Diabetes, and Nutrition, University of Maryland School of Medicine, Baltimore, MD, USA.
  • Taylor KD; Division of Endocrinology, Diabetes, and Nutrition, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA.
  • Rich SS; Division of Sleep and Circadian Disorders, Brigham and Women's Hospital, Boston, MA, USA.
  • Guo X; Cardiovascular Health Research Unit, Departments of Medicine, Epidemiology, and Health Services, University of Washington, Seattle, WA, USA.
  • Boerwinkle E; Departments of Neurology and Epidemiology, University of Washington, Seattle, WA, USA.
  • Morrison AC; Departments of Neurology and Epidemiology, University of Washington, Seattle, WA, USA.
  • Pankow JS; The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA.
  • Johnson AD; The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA.
  • Pankratz N; Center for Public Health Genomics, University of Virginia School of Medicine, Charlottesville, VA, USA.
  • Reiner AP; Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX, USA.
  • Redline S; Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX, USA.
  • Smith NL; Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX, USA.
  • Rice KM; Division of Epidemiology and Community Health, University of Minnesota, Minneapolis, MN, USA.
  • Schifano ED; Framingham Heart Study, Framingham, MA, USA.
HGG Adv ; 2(3)2021 Jul 08.
Article en En | MEDLINE | ID: mdl-34337551

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Observational_studies / Prognostic_studies / Risk_factors_studies Idioma: En Revista: HGG Adv Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Observational_studies / Prognostic_studies / Risk_factors_studies Idioma: En Revista: HGG Adv Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos