Desymmetrization of pibrentasvir for efficient prodrug synthesis.

Voight, Eric A; Greszler, Stephen N; Hartung, John; Ji, Jianguo; Klix, Russell C; Randolph, John T; Shelat, Bhadra H; Waters, Jan E; DeGoey, David A

Voight, Eric A; Greszler, Stephen N; Hartung, John; Ji, Jianguo; Klix, Russell C; Randolph, John T; Shelat, Bhadra H; Waters, Jan E; DeGoey, David A.

Afiliación

Voight EA; Drug Discovery Science & Technology, AbbVie, Inc. 1 North Waukegan Road North Chicago Illinois 60064-1802 USA eric.a.voight@abbvie.com.
Greszler SN; Drug Discovery Science & Technology, AbbVie, Inc. 1 North Waukegan Road North Chicago Illinois 60064-1802 USA eric.a.voight@abbvie.com.
Hartung J; Process Research and Development, AbbVie, Inc. 1 North Waukegan Road North Chicago Illinois 60064-1802 USA.
Ji J; Process Research and Development, AbbVie, Inc. 1 North Waukegan Road North Chicago Illinois 60064-1802 USA.
Klix RC; Process Research and Development, AbbVie, Inc. 1 North Waukegan Road North Chicago Illinois 60064-1802 USA.
Randolph JT; Drug Discovery Science & Technology, AbbVie, Inc. 1 North Waukegan Road North Chicago Illinois 60064-1802 USA eric.a.voight@abbvie.com.
Shelat BH; Process Research and Development, AbbVie, Inc. 1 North Waukegan Road North Chicago Illinois 60064-1802 USA.
Waters JE; Drug Discovery Science & Technology, AbbVie, Inc. 1 North Waukegan Road North Chicago Illinois 60064-1802 USA eric.a.voight@abbvie.com.
DeGoey DA; Drug Discovery Science & Technology, AbbVie, Inc. 1 North Waukegan Road North Chicago Illinois 60064-1802 USA eric.a.voight@abbvie.com.

Chem Sci ; 12(29): 10076-10082, 2021 Jul 28.

Article en En | MEDLINE | ID: mdl-34349971

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Chem Sci Año: 2021 Tipo del documento: Article Pais de publicación: Reino Unido

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