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FTY720 (Fingolimod), a modulator of sphingosine-1-phosphate receptors, increases baseline hypothalamic-pituitary adrenal axis activity and alters behaviors relevant to affect and anxiety.
Corbett, Brian; Luz, Sandra; Sotuyo, Nathaniel; Pearson-Leary, Jiah; Moorthy, Ganesh S; Zuppa, Athena F; Bhatnagar, Seema.
Afiliación
  • Corbett B; Center for Stress Neurobiology, Children's Hospital of Philadelphia, 3615 CIvic Center Blvd, ARC Suite 402, Philadelphia, Pennsylvania,19104-4399, USA.
  • Luz S; Center for Stress Neurobiology, Children's Hospital of Philadelphia, 3615 CIvic Center Blvd, ARC Suite 402, Philadelphia, Pennsylvania,19104-4399, USA.
  • Sotuyo N; Center for Stress Neurobiology, Children's Hospital of Philadelphia, 3615 CIvic Center Blvd, ARC Suite 402, Philadelphia, Pennsylvania,19104-4399, USA.
  • Pearson-Leary J; Center for Stress Neurobiology, Children's Hospital of Philadelphia, 3615 CIvic Center Blvd, ARC Suite 402, Philadelphia, Pennsylvania,19104-4399, USA.
  • Moorthy GS; Center for Clinical Pharmacology, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA; Department of Anesthesiology and Critical Care Medicine, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
  • Zuppa AF; Center for Clinical Pharmacology, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA; Department of Anesthesiology and Critical Care Medicine, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
  • Bhatnagar S; Center for Stress Neurobiology, Children's Hospital of Philadelphia, 3615 CIvic Center Blvd, ARC Suite 402, Philadelphia, Pennsylvania,19104-4399, USA; Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA. Electronic address: bhatnagars@chop.edu.
Physiol Behav ; 240: 113556, 2021 10 15.
Article en En | MEDLINE | ID: mdl-34390688
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Clorhidrato de Fingolimod / Sistema Hipotálamo-Hipofisario Límite: Animals Idioma: En Revista: Physiol Behav Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos
Texto completo
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XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Clorhidrato de Fingolimod / Sistema Hipotálamo-Hipofisario Límite: Animals Idioma: En Revista: Physiol Behav Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos